Epitranscriptomic analysis of m6A methylome after peripheral nerve injury

L Zhang, D Hao, P Ma, B Ma, J Qin, G Tian, Z Liu… - Frontiers in …, 2021 - frontiersin.org
N6-methyladenosine (m6A) is one of the most plentiful internal RNA modifications,
especially in eukaryotic messenger RNA (mRNA), which plays pivotal roles in the regulation …

Transcriptome-wide N6-methyladenosine methylome alteration in the rat spinal cord after acute traumatic spinal cord injury

J Yu, H Chen, H Ma, Z Zhang, X Zhu, P Wang… - Frontiers in …, 2022 - frontiersin.org
Recent studies showed that RNA N6-methyladenosine (m6A) plays an important role in
neurological diseases. We used methylated RNA immunoprecipitation sequencing (MeRIP …

Characterization of the Expressions and m6A Methylation Modification Patterns of mRNAs and lncRNAs in a Spinal Cord Injury Rat Model

X Liu, Z Li, J Tong, F Wu, H Jin, K Liu - Molecular Neurobiology, 2024 - Springer
Spinal cord injury (SCI) is a serious central nervous system disease with no effective
treatment strategy presently due to its complex pathogenic mechanism. N6 …

Epigenetic combined with transcriptomic analysis of the m6A methylome after spared nerve injury-induced neuropathic pain in mice

F Zeng, J Cao, Z Hong, Y Lu, Z Qin… - Neural Regeneration …, 2023 - journals.lww.com
Epigenetic changes in the spinal cord play a key role in the initiation and maintenance of
nerve injury-induced neuropathic pain. N6-methyladenosine (m6A) is one of the most …

Epitranscriptomic profiling of N6-methyladenosine-related RNA methylation in rat cerebral cortex following traumatic brain injury

J Yu, Y Zhang, H Ma, R Zeng, R Liu, P Wang, X Jin… - Molecular brain, 2020 - Springer
Abstract Background N6-methyladenosine (m6A) is the most prevalent post-transcriptional
modification of eukaryotic mRNA. It has been reported that there is a stimulus-dependent …

Alteration of m6A epitranscriptomic tagging of ribonucleic acids after spinal cord injury in mice

S Ni, Z Luo, Y Fan, W Zhang, W Peng… - Frontiers in …, 2022 - frontiersin.org
The m6A methylation is reported to function in multiple physiological and pathological
processes. However, the functional relevance of m6A modification to post-spinal cord …

Comprehensive analysis of m6A methylation modification in chronic spinal cord injury in mice

C Li, J Zhao, T Qin, Y Jin, C Duan, T Wu… - Journal of …, 2023 - Wiley Online Library
Chronic spinal cord injury (CSCI) is a catastrophic disease of the central nervous system
(CNS), resulting in partial or complete loss of neurological function. N6‐methyladenosine …

N6-methyladenosine RNA is modified in the rat hippocampus following traumatic brain injury with hypothermia treatment

J Cheng, L Lin, J Yu, X Zhu, H Ma, Y Zhao - Frontiers in Neuroscience, 2023 - frontiersin.org
Recent studies have suggested a role for N6-methyladenosine (m6A) modification in
neurological diseases. Hypothermia, a commonly used treatment for traumatic brain injury …

Epitranscriptomic m6A regulation following spinal cord injury

L Xing, Y Cai, T Yang, W Yu, M Gao… - Journal of …, 2021 - Wiley Online Library
RNA methylation is involved in multiple physiological and pathological processes. However,
the role of RNA methylation in spinal cord regeneration has not been reported. In this study …

Severe burn injury significantly alters the gene expression and m6A methylation tagging of mRNAs and lncRNAs in human skin

Y Ran, Z Yan, M Huang, S Zhou, F Wu, M Wang… - Journal of Personalized …, 2023 - mdpi.com
N6-methyladenosine (m6A) modulates RNA metabolism and functions in cell differentiation,
tissue development, and immune response. After acute burns, skin wounds are highly …