Background Epilepsy has long been suspected to be governed by cyclic rhythms, with
seizure rates rising and falling periodically over weeks, months, or even years. The very long …

Advances in diagnostic technology, including chronic intracranial EEG recordings, have
confirmed the clinical observation of different temporal patterns of epileptic activity and …

Importance Focal epilepsy is characterized by the cyclical recurrence of seizures, but, to our
knowledge, the prevalence and patterns of seizure cycles are unknown. Objective To …

The cyclical organization of seizures in epilepsy has been described since antiquity.
However, historical explanations for seizure cycles—based on celestial, hormonal, and …

Personalized medicine requires that treatments adapt to not only the patient but also
changing factors within each individual. Although epilepsy is a dynamic disorder …

Objective Previous studies reporting circadian patterns of epileptiform activity and seizures
are limited by (1) short‐term recording in an epilepsy monitoring unit (EMU) with altered …

Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …

Objective: The aim of this study was to determine whether seizure occurrence in partial
epilepsy is under the influence of circadian rhythms and rhythmic exogenous factors, and …

It is well known that seizures of some types of epilepsy tend to occur in patterns. The
circadian rhythm may play a significant role in this phenomenon. In animal studies it has …

Knowledge on the interaction between circadian rhythm and human epilepsy is relatively
poor, although if it exists, this interaction may be of value for better knowledge of …