[引用][C] Drug administration by aerosol in children

AL Coates, C O'Callaghan - Kendig's disorders of the respiratory tract in …, 2006 - Elsevier

Special problems in aerosol delivery: neonatal and pediatric considerations.

CH Cole - Respiratory Care, 2000 - europepmc.org
Identification of the determinants of efficient aerosol delivery and the specific challenges of
aerosol delivery to infants and children can facilitate a systematic approach to optimize …

A randomised crossover trial of facemask efficacy

JT Hayden, N Smith, DA Woolf, PW Barry… - Archives of disease in …, 2004 - adc.bmj.com
The efficacy of different facemasks that can be used in the delivery of aerosol medication to
children with recurrent wheeze or asthma was investigated. The results showed a …

Inhalation therapy in asthmatic and not asthmatic children

L Lo Valvo, S Leonardi, GL Marseglia… - International …, 2011 - journals.sagepub.com
The use of inhaled aerosols allows selective treatment of the lungs directly by achieving
high drug concentrations in the airway while reducing systemic adverse effects by …

Skin reactions to inhaled corticosteroids: Clinical aspects, incidence, avoidance, and management

B Guillot - American Journal of Clinical Dermatology, 2000 - Springer
Inhaled corticosteroids are considered by many to be the therapy of choice in the treatment
of asthma and allergic rhinitis. Systemic adverse effects are well known and are mainly dose …

Aerosol corticosteroids for the treatment of asthma

CE Johnson - Drug intelligence & clinical pharmacy, 1987 - journals.sagepub.com
In an effort to maximize the efficacy of corticosteroid treatment in asthma and minimize the
adverse reactions, steroid therapy has evolved to the inhalation route of administration with …

Addressing steroid phobia: Improving the risk–benefit ratio with new agents

JD Skoner, TJ Schaffner, CA Schad… - Allergy and asthma …, 2008 - ingentaconnect.com
Inhaled corticosteroids (ICSs) are the preferred first-line preventative therapy for asthma of
all severity levels. Although these drugs have been proven efficacious, concerns of adverse …

The delivery of inhaled medication to the young child

BK Rubin, JB Fink - Pediatric Clinics, 2003 - pediatric.theclinics.com
For more than 150 years, attempts have been made to deliver therapeutic aerosols directly
to the airways. The modern era of aerosol therapy began with the introduction of the Wright …

Aerosol delivery devices and airways/lung deposition

MB Dolovich - Inhaled Steroids in Asthma. New York, NY: Marcel …, 2001 - books.google.com
Sufficient local concentration of drug can be achieved on airway surfaces throughout the
lung by using the inhaled route. A number of factors determine the dose of drug deposited …

Inhaled and nasal corticosteroids: factors affecting the risks of systemic adverse effects

A Cave, P Arlett, E Lee - Pharmacology & therapeutics, 1999 - Elsevier
There has been increasing concern in the medical literature about the safety of inhaled and
nasal corticosteroids, since many patients, both adults and children, are increasingly …