Background Niemann-pick C1-like 1 (NPC1L1) is a key protein for intestinal cholesterol
transportation. Common single nucleotide polymorphisms (SNPs) in the NPC1L1 gene have …

Niemann–Pick type C1-like 1 (NPC1L1) protein is responsible for intestinal cholesterol
absorption. The aim of the study was to identify genetic polymorphisms of the NPC1L1 gene …

Background The association of rs16996148 single nucleotide polymorphism (SNP) in
NCAN/CILP2/PBX4 and serum lipid levels is inconsistent. Furthermore, little is known about …

A relationship between cholesterol levels and Niemann-Pick C1-Like 1 (NPC1L1)
polymorphisms in diverse populations was found in previous studies. However, relevant …

Niemann-Pick C1-like 1 (NPC1L1) protein is the key transporter responsible for dietary
cholesterol absorption. Recent studies indicated that several functional polymorphisms of …

Abstract The Niemann-Pick C1 like 1 (NPC1L1) protein is a polytopic transmembrane
protein responsible for dietary cholesterol absorption. Genetic variation in the NPC1L1 gene …

Niemann-Pick C1-like 1 protein (NPC1L1) plays a critical role in intestinal cholesterol
absorption. Our objective was to examine whether five variants (-133A> G,-18A> C, L272L …

Abstract Background Niemann-Pick C1-like 1 (NPC1L1) is involved in dietary cholesterol
absorption and is the direct molecular target of the LDL-lowering drug ezetimibe. Recently …

Cholesterol homeostasis is essential for functional integrity of lipid. Niemann-Pick disease,
type C2 (NPC2) encodes a protein containing a lipid recognition domain. NPC2 is related to …

Niemann Pick Type C1 Like 1 (NPC1L1) protein plays a key role in intestinal and hepatic
cholesterol metabolism in humans. Genetic variation in NPC1L1 has been widely studied in …