Large scale replication analysis of loci associated with lipid concentrations in a Japanese population
K Nakayama, T Bayasgalan, K Yamanaka… - Journal of medical …, 2009 - jmg.bmj.com
Background: Recent genome wide association studies discovered seven novel loci that
influence plasma concentrations of triglycerides, high density lipoprotein (HDL) and low …
influence plasma concentrations of triglycerides, high density lipoprotein (HDL) and low …
Novel gene-by-environment interactions: APOB and NPC1L1 variants affect the relationship between dietary and total plasma cholesterol [S]
DS Kim, AA Burt, JE Ranchalis, ER Jarvik… - Journal of lipid …, 2013 - ASBMB
Cardiovascular disease (CVD) is the leading cause of death in developed countries. Plasma
cholesterol level is a key risk factor in CVD pathogenesis. Genetic and dietary variation both …
cholesterol level is a key risk factor in CVD pathogenesis. Genetic and dietary variation both …
Common variants in the genes of triglyceride and HDL-C metabolism lack association with coronary artery disease in the Pakistani subjects
SU Shahid, NA Shabana, JA Cooper… - Lipids in Health and …, 2017 - Springer
Abstract Background Serum Triglyceride (TG) and High Density Lipoprotein (HDL-C) levels
are modifiable coronary artery disease (CAD) risk factors. Polymorphisms in the genes …
are modifiable coronary artery disease (CAD) risk factors. Polymorphisms in the genes …
Interactions of the apolipoprotein C-III 3238C> G polymorphism and alcohol consumption on serum triglyceride levels
Y Ruixing, L Yiyang, L Meng, L Kela… - Lipids in health and …, 2010 - Springer
Abstract Background Both apolipoprotein (Apo) C-III gene polymorphism and alcohol
consumption have been associated with increased serum triglyceride (TG) levels, but their …
consumption have been associated with increased serum triglyceride (TG) levels, but their …
Consistency between cross-sectional and longitudinal SNP: blood lipid associations
MC Costanza, S Beer-Borst, RW James… - European journal of …, 2012 - Springer
Various studies have linked different genetic single nucleotide polymorphisms (SNPs) to
different blood lipids (BL), but whether these “connections” were identified using cross …
different blood lipids (BL), but whether these “connections” were identified using cross …
Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study
L Dumitrescu, CL Carty, K Taylor, FR Schumacher… - PLOS …, 2011 - journals.plos.org
For the past five years, genome-wide association studies (GWAS) have identified hundreds
of common variants associated with human diseases and traits, including high-density …
of common variants associated with human diseases and traits, including high-density …
Dietary cholesterol reverses resistance to diet-induced weight gain in mice lacking Niemann-Pick C1-Like 1 [S]
L Jia, Y Ma, G Liu, L Yu - Journal of lipid research, 2010 - ASBMB
Niemann-Pick C1-Like 1 (NPC1L1) mediates intestinal cholesterol absorption. NPC1L1
knockout (L1-KO) mice were recently shown to be resistant to high-fat diet (HFD)-induced …
knockout (L1-KO) mice were recently shown to be resistant to high-fat diet (HFD)-induced …
Association of genetic variants with dyslipidemia
S Abe, F Tokoro, R Matsuoka… - Molecular …, 2015 - spandidos-publications.com
Although genetic variants, which regulate lipid metabolism, have been extensively
investigated in Caucasian populations, the genes, which confer susceptibility to …
investigated in Caucasian populations, the genes, which confer susceptibility to …
d-Glucose modulates intestinal Niemann-Pick C1-like 1 (NPC1L1) gene expression via transcriptional regulation
P Malhotra, CS Boddy, V Soni… - American Journal …, 2013 - journals.physiology.org
The expression of intestinal Niemann-Pick C1-like 1 (NPC1L1) cholesterol transporter has
been shown to be elevated in patients with diseases associated with hypercholesterolemia …
been shown to be elevated in patients with diseases associated with hypercholesterolemia …
Interactive effects of C-reactive protein levels on the association between APOE variants and triglyceride levels in a Taiwanese population
S Wu, LA Hsu, MS Teng, JF Lin, HH Chou… - Lipids in health and …, 2016 - Springer
Abstract Background Apolipoprotein E (APOE) plays a major role in lipid metabolism and
inflammation. However, the association between APOE gene polymorphisms and serum …
inflammation. However, the association between APOE gene polymorphisms and serum …