Knowledge about the conversion of the epithelium in the distal air spaces of the lung from
secretion to absorption is imperative to the understanding of postnatal lung development; …

It has been shown that short-term (hours) treatment with β-adrenergic agonists can stimulate
lung liquid clearance via augmented Na+ transport across alveolar epithelial cells. This …

Analysis of membrane currents recorded from hormone-deprived H441 cells showed that
the membrane potential (V m) in single cells (approximately− 80 mV) was unaffected by …

In pulmonary epithelia, β-adrenergic agonists regulate the membrane abundance of the
epithelial sodium channel (ENaC) and, thereby, control the rate of transepithelial electrolyte …

cAMP and dexamethasone are known to modulate Na+ transport in epithelial cells. We
investigated whether dibutyryl cAMP (DBcAMP) and dexamethasone modulate the mRNA …

Abstract Background Antenatal glucocorticoids (GCs) reduce respiratory distress syndrome
(RDS) in preterm infants and are associated with reduced lung liquid content. Our aim was …

Treating H441 cells with dexamethasone raised the abundance of mRNA encoding the
epithelial Na+ channel α-and β-subunits and increased transepithelial ion transport …

The newborn lung exhibits many sex-specific differences during development, post-natal
transition, and in the manifestation of neonatal lung diseases. These differences are evident …

Male sex is considered an independent predictor for the development of bronchopulmonary
dysplasia (BPD) after adjusting for other confounders. BPD is characterized by an arrest in …

Hypoxia and epithelial stretch that are commonly observed in patients with acute lung injury
have been shown to promote the release of serotonin (5-hydroxytryptamine, 5-HT) in vitro …