Gene disruption by biolistic transformation in serotype D strains of Cryptococcus
neoformans. Fungal Genetics and Biology29, 38–48. Cryptococcus neoformans is an …

Cryptococcosis is a major threat to immunocompromised individuals. Isolates of
Cryptococcus neoformans var. grubii and var. neoformans are responsible for most of the …

Gene disruption in Cryptococcus neoformans can be problematic due to high frequencies of
ectopic integration and telomerization. To improve the frequency of homologous integration …

Cryptococcus neoformans is an opportunistic fungal pathogen with a defined sexual cycle
for which genetic and molecular techniques are well developed. The entire genome …

▪ Abstract Cryptococcus neoformans is a pathogenic fungus that primarily afflicts
immunocompromised patients, infecting the central nervous system to cause …

Cryptococcus neoformans is a pathogenic fungus that is relatively amenable to molecular
genetic analysis, including gene deletion. However, rates of homologous recombination can …

Cryptococcus neoformans has two varieties, var. grubii and var. neoformans, that
correspond to serotypes A and D, respectively. Molecular phylogenetic analyses suggest …

Just as Koch's postulates formed the foundation of early infectious disease study, Stanley
Falkow's molecular Koch's postulates define best practice in determining whether a specific …

Cryptococcus neoformans is a major human pathogenic fungus that can cause
meningoencephalitis in immunocompromised hosts. It contains two divergent varieties, var …

The availability of the whole-genome sequence from the 2 known varieties of the human
pathogenic fungus Cryptococcus neoformans provides an opportunity to study the relative …