Synthesis and biological evaluation of novel 2, 4-disubstituted-1, 3-thiazoles as anti-Candida spp. agents

F Chimenti, B Bizzarri, A Bolasco, D Secci… - European journal of …, 2011 - Elsevier
A new series of [4-(4′-substituted-phenyl) thiazol-2-yl] hydrazine derivatives were
synthesized in good yield (86–99%) and characterized by elemental analysis, IR, 1H NMR …

Synthesis and cytotoxicity of novel (thiazol-2-yl) hydrazine derivatives as promising anti-Candida agents

S Carradori, D Secci, A Bolasco, D Rivanera… - European Journal of …, 2013 - Elsevier
Abstract Thirty-eight new (4-(4-substituted-phenyl/2, 4-disubstituted-phenyl)-thiazol-2-yl)
hydrazine derivatives were synthesized in good yield and assayed for their in vitro anti …

Synthesis, anti-Candida activity, and cytotoxicity of new (4-(4-iodophenyl) thiazol-2-yl) hydrazine derivatives

D Secci, B Bizzarri, A Bolasco, S Carradori… - European journal of …, 2012 - Elsevier
Novel (4-(4-iodophenyl)-thiazol-2-yl) hydrazine derivatives were assayed for their in vitro
anti-Candida activity, compared to topical and systemic antifungal drugs, against twenty …

Synthesis and in vitro activity of 2-thiazolylhydrazone derivatives compared with the activity of clotrimazole against clinical isolates of Candida spp.

F Chimenti, B Bizzarri, E Maccioni, D Secci… - Bioorganic & medicinal …, 2007 - Elsevier
In this paper, we report on the synthesis of a novel series of 2-thiazolylhydrazone derivatives
and the influence of the substituents on the thiazole ring on antifungal activity. All …

Synthesis and anti-Candida activity of novel 2-hydrazino-1, 3-thiazole derivatives

LT Maillard, S Bertout, O Quinonéro, G Akalin… - Bioorganic & medicinal …, 2013 - Elsevier
Eighteen new hydrazino-1, 3-thiazole derivatives were evaluated against 8 strains of multi-
resistant Candida spp. Introduction of an indolyl moiety linked to the hydrazone function …

[HTML][HTML] Synthesis and in vitro evaluation of new nitro-substituted thiazolyl hydrazone derivatives as anticandidal and anticancer agents

MD Altıntop, A Özdemir, G Turan-Zitouni, S Ilgın, Ö Atlı… - Molecules, 2014 - mdpi.com
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their
anticandidal activity using a broth microdilution assay. Among the synthesized compounds …

Synthesis, antimicrobial activity, and determination of the lipophilicity of ((cyclohex-3-enylmethylene) hydrazinyl) thiazole derivatives

A Biernasiuk, M Kawczyńska, A Berecka-Rycerz… - Medicinal Chemistry …, 2019 - Springer
Synthesis and investigation of antimicrobial activity of fifteen novel thiazoles containing
cyclohexene moiety are presented. Among the derivatives, compounds 3a–3d, 3f, 3n, and …

Novel 1, 3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties

D Secci, S Carradori, B Bizzarri, P Chimenti… - European Journal of …, 2016 - Elsevier
Pursuing our recent outcomes regarding the antifungal activity of N-substituted 1, 3-
thiazolidin-4-ones, we synthesized thirty-six new derivatives introducing aliphatic …

Synthesis and antimicrobial activity of 4-phenyl/cyclohexyl-5-(1-phenoxyethyl)-3-[N-(2-thiazolyl) acetamido] thio-4H-1, 2, 4-triazole derivatives

G Turan-Zitouni, ZA Kaplancıklı, MT Yıldız… - European journal of …, 2005 - Elsevier
The increasing clinical importance of drug-resistant fungal and bacterial pathogens has lent
additional urgency to microbiological research and new antimicrobial compound …

[PDF][PDF] Synthesis, Characterization and antifungal activity of certain (E)-1-(1-(substitutedphenyl) ethylidene)-2-(6-methylbenzo [d] thiazol-2-yl) hydrazine analogues

G Alang, R Kaur, A Singh, P Budhlakoti, A Singh… - International Journal of …, 2010 - Citeseer
In the present study, five new derivatives (R1 to R5) of benzothiazoles were synthesized and
were evaluated against four fungal strains: Candida albicans (MTCC 183), Aspergillus niger …