Reactive oxygen species are not only harmful agents that cause oxidative damage in
pathologies, they also have important roles as regulatory agents in a range of biological …

Multiple roles of reactive oxygen species (ROS) and their consequences for health and
disease are emerging throughout biological sciences. This development has led …

Although oxidants clearly possess the capacity to behave in a random and destructive
fashion, growing evidence suggests that in many instances the production of reactive …

Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

Abstract Since the Great Oxidation Event, about 2.4 billion years ago, the Earth is immersed
in an oxidizing atmosphere. Thus, it has been proposed that excess oxygen, originally a …

Living species are continuously subjected to all extrinsic forms of reactive oxidants and
others that are produced endogenously. There is extensive literature on the generation and …

Reactive oxygen species (ROS) are chemically reactive molecules that are naturally
produced within biological systems. Research has focused extensively on revealing the …

Thirty-five years ago, Sies and colleagues insightfully described the universal phenomenon
that the generation of reactive oxygen species could modify macromolecules in living …

Reactive species are highly-reactive enzymatically, or non-enzymatically produced
compounds with important roles in physiological and pathophysiological cellular processes …

Significance: Enhanced levels of reactive oxygen species (ROS) have been associated with
different disease states. Most attempts to validate and exploit these associations by chronic …