Chondroitin sulfate proteoglycans in the nervous system: inhibitors to repair
JR Siebert, A Conta Steencken… - BioMed research …, 2014 - Wiley Online Library
Chondroitin sulfate proteoglycans (CSPGs) are widely expressed in the normal central
nervous system, serving as guidance cues during development and modulating synaptic …
nervous system, serving as guidance cues during development and modulating synaptic …
Chondroitin sulfate proteoglycans: Key modulators in the developing and pathologic central nervous system
SM Dyck, S Karimi-Abdolrezaee - Experimental neurology, 2015 - Elsevier
Abstract Chondroitin Sulfate Proteoglycans (CSPGs) are a major component of the
extracellular matrix in the central nervous system (CNS) and play critical role in the …
extracellular matrix in the central nervous system (CNS) and play critical role in the …
The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system
CM Galtrey, JW Fawcett - Brain research reviews, 2007 - Elsevier
Chondroitin sulfate proteoglycans (CSPGs) consist of a core protein and glycosaminoglycan
(GAG) chains. There is enormous structural diversity among CSPGs due to variation in the …
(GAG) chains. There is enormous structural diversity among CSPGs due to variation in the …
Chondroitin sulphate proteoglycans: key modulators of spinal cord and brain plasticity
Chondroitin sulphate proteoglycans (CSPGs) are a family of inhibitory extracellular matrix
molecules that are highly expressed during development, where they are involved in …
molecules that are highly expressed during development, where they are involved in …
Targeting chondroitin sulfate proteoglycans: an emerging therapeutic strategy to treat CNS injury
Chondroitin sulfate proteoglycans (CSPGs) are the most abundant components of glial scar
formed after severe traumatic brain injury as well as spinal cord injury and play a crucial …
formed after severe traumatic brain injury as well as spinal cord injury and play a crucial …
[HTML][HTML] Two faces of chondroitin sulfate proteoglycan in spinal cord repair: a role in microglia/macrophage activation
A Rolls, R Shechter, A London, Y Segev… - PLoS …, 2008 - journals.plos.org
Background Chondroitin sulfate proteoglycan (CSPG) is a major component of the glial scar.
It is considered to be a major obstacle for central nervous system (CNS) recovery after injury …
It is considered to be a major obstacle for central nervous system (CNS) recovery after injury …
Inhibiting glycosaminoglycan chain polymerization decreases the inhibitory activity of astrocyte-derived chondroitin sulfate proteoglycans
TL Laabs, H Wang, Y Katagiri, T McCann… - Journal of …, 2007 - Soc Neuroscience
Chondroitin sulfate proteoglycans (CSPGs) are upregulated in the CNS after injury and
participate in the inhibition of axon regeneration mainly through their glycosaminoglycan …
participate in the inhibition of axon regeneration mainly through their glycosaminoglycan …
A disaccharide derived from chondroitin sulphate proteoglycan promotes central nervous system repair in rats and mice†
A Rolls, H Avidan, L Cahalon, H Schori… - European Journal of …, 2004 - Wiley Online Library
Chondroitin sulphate proteoglycan (CSPG) inhibits axonal regeneration in the central
nervous system (CNS) and its local degradation promotes repair. We postulated that the …
nervous system (CNS) and its local degradation promotes repair. We postulated that the …
Mechanisms for modulation of neural plasticity and axon regeneration by chondroitin sulphate
S Miyata, H Kitagawa - The journal of biochemistry, 2015 - academic.oup.com
Chondroitin sulphate proteoglycans (CSPGs), consisting of core proteins linked to one or
more chondroitin sulphate (CS) chains, are major extracellular matrix (ECM) components of …
more chondroitin sulphate (CS) chains, are major extracellular matrix (ECM) components of …
Chondroitin sulfate proteoglycans in neural development and regeneration
T Laabs, D Carulli, HM Geller, JW Fawcett - Current opinion in …, 2005 - Elsevier
Proteoglycans are of two main types, chondroitin sulfate (CSPGs) and heparin sulfate
(HSPGs). The CSPGs act mainly as barrier-forming molecules, whereas the HSPGs stabilise …
(HSPGs). The CSPGs act mainly as barrier-forming molecules, whereas the HSPGs stabilise …