Canine mast cell tumours part I: Clinical and survival outcomes

VS Tamlin, CDK Bottema, L Woolford… - Veterinary Medicine …, 2022 - Wiley Online Library
Background Dogs have a species‐specific susceptibility for developing mast cell tumours
(MCTs). Mutations in the KIT proto‐oncogene (KIT) are known to contribute to the neoplastic …

Canine subcutaneous mast cell tumors: cellular proliferation and KIT expression as prognostic indices

JJ Thompson, JA Yager, SJ Best… - Veterinary …, 2011 - journals.sagepub.com
Molecular assays are widely used to prognosticate canine cutaneous mast cell tumors
(MCT). There is limited information about these prognostic assays used on MCT that arise in …

Prevalence and prognostic value of c-kit and TP53 mutations in canine mast cell tumours

M Vozdova, S Kubickova, P Fictum, J Fröhlich… - The Veterinary …, 2019 - Elsevier
Cutaneous mast cell tumours (MCT) are among the most frequent malignancies in dogs.
Their clinical behaviour is highly variable and, with the exception of mutations in the c-kit …

Validation of the prognostic value of histopathological grading or c-kit mutation in canine cutaneous mast cell tumours: a retrospective cohort study

Y Takeuchi, Y Fujino, M Watanabe, M Takahashi… - The Veterinary …, 2013 - Elsevier
The objective of this retrospective cohort study was to validate the prognostic value of
histological grading of canine cutaneous mast cell tumours (MCTs) according to the Patnaik …

Mast cell tumours in dogs less than 12 months of age: a multi‐institutional retrospective study

K Rigas, D Biasoli, G Polton, R Finotello… - Journal of Small …, 2020 - Wiley Online Library
Objectives To describe the clinicopathological and genetic characteristics of mast cell
tumours in dogs less than 12 months old. Materials and Methods Retrospective review of …

The use of KIT and tryptase expression patterns as prognostic tools for canine cutaneous mast cell tumors

M Kiupel, JD Webster, JB Kaneene… - Veterinary …, 2004 - journals.sagepub.com
Cutaneous mast cell tumors (MCTs) are one of the most common tumors in dogs. Currently,
prognostic and therapeutic determinations for MCTs are primarily based on the histologic …

Histologic grading of canine mast cell tumor: is 2 better than 3?

S Sabattini, F Scarpa, D Berlato… - Veterinary …, 2015 - journals.sagepub.com
Mast cell tumor (MCT) is a common canine cutaneous neoplasm with variable biological
behavior. A 2-tier histologic grading system was recently proposed by Kiupel et al to reduce …

[HTML][HTML] Evaluation of prognostic markers for canine mast cell tumors treated with vinblastine and prednisone

JD Webster, V Yuzbasiyan-Gurkan, DH Thamm… - BMC veterinary …, 2008 - Springer
Background Canine cutaneous mast cell tumor (MCT) is a common neoplastic disease
associated with a variable biologic behavior. Surgery remains the primary treatment for …

[HTML][HTML] Immunohistochemical and molecular genetic analysis of canine digital mast cell tumours

D Conrad, A Kehl, T Müller, R Klopfleisch… - Animals, 2023 - mdpi.com
Simple Summary In veterinary medicine, methods such as histological grading,
immunohistochemistry and mutation analysis of the c-kit gene are tools to assess the …

Features and prognostic impact of distant metastases in 45 dogs with de novo stage IV cutaneous mast cell tumours: A prospective study

S Pizzoni, S Sabattini, D Stefanello… - Veterinary and …, 2018 - Wiley Online Library
Background Distant metastases in dogs with cutaneous mast cell tumors (cMCT) are rare
and incurable. The aims of this prospective study were to clarify the clinico‐pathological …