Background The involvement of the nerve in psoriasis development was suggested by
sporadic case reports. Objectives To provide multiple evidence for the nerve in psoriasis …

Nervous system involvement in psoriasis pathogenesis is supported by increases in nerve
fiber numbers and neuropeptides in psoriatic skin and by reports detailing spontaneous …

Recent studies have illustrated that psoriatic lesions are innervated by dense sensory nerve
fibers. Psoriatic plaques appeared to improve after central or peripheral nerve injury …

Linear psoriasis following the typical distribution of the sciatic nerve - PMC Back to Top Skip to
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Psoriasis is a chronic inflammatory skin disease with a prevalence of 2–3%. It appears to
result from a combination of genetic and environmental factors, but the precise pathogenesis …

Psoriasis is characterized by keratinocyte hyperproliferation, erythema, as well as a form of
pruritus, involving cutaneous discomfort. There is evidence from both clinical and murine …

As most efforts in the last decade have focused on the immunologic basis of inflammatory
skin disease, there has been less emphasis on the role of the nervous system in the disease …

Psoriasis is a chronic inflammatory skin disease presenting with an array of clinical
phenotypes, often associated with pruritus. Environmental and psychological stressors can …

Psoriasis is a chronic immune-mediated skin disorder with the nervous system contributing
to its pathology. The neurogenic mediators of psoriasis are elusive, and whether the …

TNF-α, a proinflammatory cytokine, is a crucial mediator of psoriasis pathogenesis. TNF-α
functions by activating TNFR1 and TNFR2. Anti-TNF drugs that neutralize TNF-α, thus …