Mitochondria are an essential component of multicellular life–from primitive organisms, to
highly complex entities like mammals. The importance of mitochondria is underlined by their …

Another view is that mitochondrial fusion allows for genetic complementation between 2
mitochondria, which promotes ATP synthesis in oxygen-deprived regions of a cell through …

Mitochondrial dysfunction is considered as a crucial contributory factor in cardiac pathology.
This has highlighted the therapeutic potential of targeting mitochondria to prevent or treat …

There remains an unmet need to identify novel therapeutic strategies capable of protecting
the myocardium against the detrimental effects of acute ischemia–reperfusion injury (IRI), to …

Mitochondria are critical for sustaining life, not only as the essential powerhouses of cells but
as critical mediators of cell survival and death. Mitochondrial dysfunction has been identified …

The mitochondrion is a vital component in cellular energy metabolism and intracellular
signaling processes. Mitochondria are involved in a myriad of complex signaling cascades …

Mitochondrial dynamics is a recent topic of research in the field of cardiac physiology. The
study of mechanisms involved in the morphological changes and in the mobility of …

Mitochondria are dynamic organelles able to vary their morphology between elongated
interconnected mitochondrial networks and fragmented disconnected arrays, through events …

Cardiac mitochondria, the main source of energy as well as free radicals, are vital
organelles for normal functioning of the heart. Mitochondrial number, structure, turnover and …

Mitochondrial damage is a critical contributor to cardiac ischemia/reperfusion (I/R) injury.
Mitochondrial quality control (MQC) mechanisms, a series of adaptive responses that …