Recombination between sindbis virus RNAs
BG Weiss, S Schlesinger - Journal of virology, 1991 - Am Soc Microbiol
The genome (49S RNA) of Sindbis virus is a positive-strand RNA of 11.7 kb that consists of
two domains. The 5'two-thirds of the RNA codes for the proteins required for replication and …
two domains. The 5'two-thirds of the RNA codes for the proteins required for replication and …
Alphavirus vectors for cancer gene therapy
R Yamanaka - International journal of oncology, 2004 - spandidos-publications.com
Alphaviruses have several characteristics that make them attractive as gene therapy vectors
such as transient and high-level expression of a heterologous gene. Alphavirus vectors …
such as transient and high-level expression of a heterologous gene. Alphavirus vectors …
Oncolytic Sindbis virus targets tumors defective in the interferon response and induces significant bystander antitumor immunity in vivo
PY Huang, JH Guo, LH Hwang - Molecular Therapy, 2012 - cell.com
Sindbis virus (SBV) has been shown to possess oncolytic potential in many human
xenograft tumor models in immunocompromised mice. However, the mechanism underlying …
xenograft tumor models in immunocompromised mice. However, the mechanism underlying …
Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions
CM Rice, CA Franke, JH Strauss, DE Hruby - Journal of virology, 1985 - Am Soc Microbiol
We have obtained a vaccinia virus recombinant which contains a complete cDNA copy of
the 26S RNA of Sindbis virus within the thymidine kinase gene of the vaccinia virus genome …
the 26S RNA of Sindbis virus within the thymidine kinase gene of the vaccinia virus genome …
Antiapoptosis chemicals prolong productive lifetimes of mammalian cells upon Sindbis virus vector infection
AJ Mastrangelo, S Zou, JM Hardwick… - Biotechnology and …, 1999 - Wiley Online Library
Viral expression systems allow for the rapid production of large amounts of recombinant
protein in cell culture. In particular, Sindbis virus vectors now exist that make possible the …
protein in cell culture. In particular, Sindbis virus vectors now exist that make possible the …
Attenuation of Sindbis virus neurovirulence by using defined mutations in nontranslated regions of the genome RNA
RJ Kuhn, DE Griffin, H Zhang, HG Niesters… - Journal of …, 1992 - Am Soc Microbiol
We examined a panel of Sindbis virus mutants containing defined mutations in the
5'nontranslated region of the genome RNA, in the 3'nontranslated region, or in both for their …
5'nontranslated region of the genome RNA, in the 3'nontranslated region, or in both for their …