Dissolvable polymer microneedles for drug delivery and diagnostics

M Ali, S Namjoshi, HAE Benson, Y Mohammed… - Journal of Controlled …, 2022 - Elsevier
Dissolvable transdermal microneedles (μND) are promising micro-devices used to transport
a wide selection of active compounds into the skin. To provide an effective therapeutic …

A patchless dissolving microneedle delivery system enabling rapid and efficient transdermal drug delivery

SF Lahiji, M Dangol, H Jung - Scientific reports, 2015 - nature.com
Dissolving microneedles (DMNs) are polymeric, microscopic needles that deliver
encapsulated drugs in a minimally invasive manner. Currently, DMN arrays are …

[HTML][HTML] Dissolving microneedles: Applications and growing therapeutic potential

Z Sartawi, C Blackshields, W Faisal - Journal of Controlled Release, 2022 - Elsevier
Microneedles are a rapidly developing method for the transdermal delivery of therapeutic
compounds. All types of microneedles, whether solid, hollow, coated, or dissolving function …

Recent advances in microneedle platforms for transdermal drug delivery technologies

S Mdanda, P Ubanako, PPD Kondiah, P Kumar… - Polymers, 2021 - mdpi.com
In many clinical applications, the transdermal route is used as an alternative approach to
avoid the significant limitations associated with oral drug delivery. There is a long history for …

Dissolving microneedles for transdermal drug delivery: Advances and challenges

K Ita - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Over the last number of years, a significant body of evidence has shown the benefit of using
dissolving microneedles (DMNs) for transdermal drug delivery. These devices are prepared …

Dissolving microneedles for transdermal drug delivery

JW Lee, JH Park, MR Prausnitz - Biomaterials, 2008 - Elsevier
Microfabrication technology has been adapted to produce micron-scale needles as a safer
and painless alternative to hypodermic needle injection, especially for protein …

Recent advances in polymer microneedles for drug transdermal delivery: Design strategies and applications

R Wang, G Jiang, UE Aharodnikau… - Macromolecular …, 2022 - Wiley Online Library
In recent years, transdermal drug delivery based on microneedles (MNs) technology has
received extensive attention, which offers a safer and painless alternative to hypodermic …

Micro-pillar integrated dissolving microneedles for enhanced transdermal drug delivery

S Lee, S Fakhraei Lahiji, J Jang, M Jang, H Jung - Pharmaceutics, 2019 - mdpi.com
The dissolving microneedle (DMN) patch is a transdermal delivery system, containing arrays
of micro-sized polymeric needles capable of encapsulating therapeutic drugs within their …

Rapidly separating microneedles for transdermal drug delivery

DD Zhu, QL Wang, XB Liu, XD Guo - Acta biomaterialia, 2016 - Elsevier
The applications of polymer microneedles (MNs) into human skin emerged as an alternative
of the conventional hypodermic needles. However, dissolving MNs require many minutes to …

Polymeric microneedles for controlled transdermal drug delivery

P Singh, A Carrier, Y Chen, S Lin, J Wang, S Cui… - Journal of controlled …, 2019 - Elsevier
Polymeric microneedle (MN) systems are interesting transdermal drug delivery systems
because of their controlled drug delivery, tunable properties, and ease of patient self …