Serotonin and the immune system

A Roumier, C Béchade, L Maroteaux - Serotonin, 2019 - Elsevier
The defense against pathogens is mediated by innate and adaptive immune mechanisms
that act in periphery and central nervous system (CNS). Outside the CNS, serotonin is found …

Serotonin: a review

LF Mohammad‐Zadeh, L Moses… - Journal of veterinary …, 2008 - Wiley Online Library
5‐Hydroxytryptamine, or serotonin, is a biogenic amine most noted for its role as a
neurotransmitter. Manipulation of serotonin in animal models was used as a tool for studying …

The serotonin transporter is present and functional in peripheral arterial smooth muscle

W Ni, JM Thompson, CA Northcott… - Journal of …, 2004 - journals.lww.com
We tested the hypothesis that the 5-HT transporter (5-HTT) is present and functional in
peripheral arterial smooth muscle. In aorta and mesenteric resistance arteries, real time RT …

Dual Serotonergic Regulation of Ventricular Contractile Force Through 5-HT2A and 5-HT4 Receptors Induced in the Acute Failing Heart

E Qvigstad, I Sjaastad, T Brattelid, C Nunn… - Circulation …, 2005 - Am Heart Assoc
Cardiac responsiveness to neurohumoral stimulation is altered in congestive heart failure
(CHF). In chronic CHF, the left ventricle has become sensitive to serotonin because of …

Serotonin and cancer: what is the link?

D Sarrouilhe, J Clarhaut, N Defamie… - Current molecular …, 2015 - ingentaconnect.com
Serotonin (5-hydroxytryptamine, 5-HT) is a biogenic monoamine that acts as a
neurotransmitter in the central nervous system, local mediator in the gut and vasoactive …

Serotonin-induced hypercontraction through 5-hydroxytryptamine 1B receptors in atherosclerotic rabbit coronary arteries

T Ishida, S Kawashima, K Hirata, T Sakoda… - Circulation, 2001 - Am Heart Assoc
Background—Augmented vasoconstriction to serotonin (5-hydroxytryptamine [5-HT]) in
atherosclerotic vessels plays a crucial role in the development of myocardial ischemia. We …

The role of serotonin in the pathophysiology of depression: as important as ever

CB Nemeroff, MJ Owens - Clinical chemistry, 2009 - academic.oup.com
Fifteen years have elapsed since we published this article focusing on the serotonin
transporter (SERT) 3. Although developed as a review, this report ultimately included …

Serotonergic receptor subtypes and vascular reactivity

JM Van Nueten, JE Leysen, F De Clerck… - Journal of …, 1984 - journals.lww.com
Two distinct binding sites for serotonin have been identified in brain tissue and labeled 5-HT
1 and 5-HT 2 binding sites. The receptor mediating contractions of several types of vascular …

Serotonin, 5-HT2 receptors, and their blockade by naftidrofuryl: a targeted therapy of vascular diseases

NF Wiernsperger - Journal of cardiovascular pharmacology, 1994 - journals.lww.com
The importance and the various effects of serotonin (5-HT) in cardiovascular diseases are
reviewed, with particular emphasis on the involvement of 5-HT 2 receptors as mediators of …

Serotonin and vasoconstrictor synergism

O Yildiz, JR Smith, RE Purdy - Life sciences, 1998 - Elsevier
Contractile synergism between serotonin (5-hydroxytryptamine, 5-HT) and other
vasoconstrictor substances has been observed in a number of peripheral and …