[HTML][HTML] Oral immunotherapy and basophil and mast cell reactivity in food allergy

A Paranjape, M Tsai, K Mukai, RA Hoh… - Frontiers in …, 2020 - frontiersin.org
Basophil activation tests (BATs) can closely monitor, in vitro, a patient's propensity to
develop type I hypersensitivity reactions. Because of their high specificity and sensitivity …

Road map for the clinical application of the basophil activation test in food allergy

AF Santos, WG Shreffler - Clinical & Experimental Allergy, 2017 - Wiley Online Library
The diagnosis of IgE‐mediated food allergy based solely on the clinical history and the
documentation of specific IgE to whole allergen extract or single allergens is often …

The basophil activation test for clinical management of food allergies: recent advances and future directions

D Briceno Noriega, M Teodorowicz… - Journal of Asthma …, 2021 - Taylor & Francis
The basophil activation test (BAT) is an ex vivo functional assay that measures by flow
cytometry the degree of basophil degranulation after stimulation with an allergen. In recent …

Basophil activation test in the food allergy clinic: its current use and future applications

MM Bergmann, AF Santos - Expert Review of Clinical Immunology, 2024 - Taylor & Francis
Introduction The basophil activation test (BAT) has shown evidence of high sensitivity and
high specificity to support the diagnosis of IgE-mediated allergy. It is a functional test that …

Mast cells in food allergy: Inducing immediate reactions and shaping long-term immunity

HC Oettgen - Journal of Allergy and Clinical Immunology, 2023 - Elsevier
Mast cells are distributed throughout the gastrointestinal tract and function as the main
effector cells of IgE-mediated allergic reactions to foods. Allergen-induced cross-linking of …

[HTML][HTML] Basophil activation test: food challenge in a test tube or specialist research tool?

AF Santos, G Lack - Clinical and translational allergy, 2016 - Springer
Oral food challenge (OFC) is the gold-standard to diagnose food allergy; however, it is a
labour and resource-intensive procedure with the risk of causing an acute allergic reaction …

[PDF][PDF] Basophil activation tests in food allergy

DG Ebo - Clinical & Experimental Allergy, 2009 - researchgate.net
The 'gold standard'for diagnosis of IgE-mediated food allergy remains a properly performed
double-blind, placebo-controlled food challenge (DBPCFC)[1, 2]. However, there are …

[HTML][HTML] Intestinal mast cell levels control severity of oral antigen-induced anaphylaxis in mice

R Ahrens, H Osterfeld, D Wu, CY Chen… - The American journal of …, 2012 - Elsevier
Food-triggered anaphylaxis can encompass a variety of symptoms that affect multiple organ
systems and can be life threatening. The molecular distinction between non–life-threatening …

Mast cell versus basophil activation test in allergy: Current status

DG Ebo, R Bahri, C Tontini… - Clinical & …, 2024 - Wiley Online Library
In the past two decades, we witnessed the evolution of the basophil activation test (BAT)
from mainly research applications to a potential complementary diagnostic tool to document …

Basophil activation test in food allergy: is it ready for real-time?

T Keswani, SU Patil - Current opinion in allergy and clinical …, 2021 - journals.lww.com
Basophil activation test in food allergy: is it ready for re... : Current Opinion in Allergy and
Clinical Immunology Basophil activation test in food allergy: is it ready for real-time? : Current …