[HTML][HTML] Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential
Drug delivery systems or vectors are usually needed to improve the bioavailability and
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …
Poly (amidoamine)(PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications
R Esfand, DA Tomalia - Drug discovery today, 2001 - Elsevier
Poly (amidoamine)(PAMAM) dendrimers are the first complete dendrimer family to be
synthesized, characterized and commercialized. Based on this extensive activity, they are …
synthesized, characterized and commercialized. Based on this extensive activity, they are …
Dendrimer‐based nanocarriers: a versatile platform for drug delivery
Advances in nanotechnology have had profound impacts on therapeutic delivery, leading to
the development of nanomaterials engineered with large carrying capabilities and targeting …
the development of nanomaterials engineered with large carrying capabilities and targeting …
Transepithelial transport and toxicity of PAMAM dendrimers: implications for oral drug delivery
S Sadekar, H Ghandehari - Advanced drug delivery reviews, 2012 - Elsevier
This article summarizes efforts to evaluate poly (amido amine)(PAMAM) dendrimers as
carriers for oral drug delivery. Specifically, the effect of PAMAM generation, surface charge …
carriers for oral drug delivery. Specifically, the effect of PAMAM generation, surface charge …
PAMAM dendrimer as a talented multifunctional biomimetic nanocarrier for cancer diagnosis and therapy
B Surekha, NS Kommana, SK Dubey… - Colloids and Surfaces B …, 2021 - Elsevier
Abstract Poly (amidoamine) dendrimers (PAMAM) are novel polymeric highly branched
architectures with well-defined nano-size, narrow polydispersity index and numerous active …
architectures with well-defined nano-size, narrow polydispersity index and numerous active …
Surface acetylation of polyamidoamine (PAMAM) dendrimers decreases cytotoxicity while maintaining membrane permeability
RB Kolhatkar, KM Kitchens, PW Swaan… - Bioconjugate …, 2007 - ACS Publications
Improving the oral bioavailability of therapeutic compounds remains a challenging area of
research. Polyamidoamine (PAMAM) dendrimers are promising candidates for oral drug …
research. Polyamidoamine (PAMAM) dendrimers are promising candidates for oral drug …
[HTML][HTML] New advances in general biomedical applications of PAMAM dendrimers
Dendrimers are nanoscopic compounds, which are monodispersed, and they are generally
considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by …
considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by …
PAMAM dendrimers: destined for success or doomed to fail? Plain and modified PAMAM dendrimers in the context of biomedical applications
M Labieniec-Watala, C Watala - Journal of pharmaceutical sciences, 2015 - Elsevier
PAMAM (polyamidoamine) dendrimers are commonly considered promising polymers that
can be successfully used in various biomedical applications. Nevertheless, direct clinical …
can be successfully used in various biomedical applications. Nevertheless, direct clinical …
PEGylated PAMAM dendrimers: Enhancing efficacy and mitigating toxicity for effective anticancer drug and gene delivery
Abstract Poly (amidoamine) dendrimers (PAMAM) are well-defined, highly branched,
nanoscale macromolecules with numerous active amine groups on the surface. PAMAM …
nanoscale macromolecules with numerous active amine groups on the surface. PAMAM …
[HTML][HTML] Modified carboxyl-terminated PAMAM dendrimers as great cytocompatible nano-based drug delivery system
MT Vu, LG Bach, DC Nguyen, MN Ho… - International journal of …, 2019 - mdpi.com
Polyamidoamine (PAMAM) dendrimers are extensively researched as potential drug
delivery system thanks to their desirable features such as controlled and stable structures …
delivery system thanks to their desirable features such as controlled and stable structures …
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