Influenza A virus (IAV) is a major respiratory pathogen that causes seasonal and pandemic
flu, being a threat to global health. Various viral and cellular factors have been characterized …

Influenza A virus (IAV) is the major cause of seasonal epidemics and flu outbreaks
worldwide. Given that interleukin 16 (IL16) can regulate T cell function and is one of the …

Influenza A virus (IAV) has developed elegant strategies to utilize cellular proteins and
pathways to promote replication and evade the host antiviral response. Identification of …

Pro-inflammatory cytokinemia is a hallmark of highly pathogenic H5N1 influenza virus (IAV)
disease yet little is known about the role of host proteins in modulating a pathogenic innate …

ABSTRACT Interleukin-22 (IL-22) has redundant, protective, or pathogenic functions during
autoimmune, inflammatory, and infectious diseases. Here, we addressed the potential role …

The acute inflammatory lung injury is an important cause of death due to influenza A virus
(IAV) infection. Insulin-like growth factor 1 (IGF1) played an important role in the regulation of …

Influenza A virus (IAV) infection is a major worldwide public health problem. However, the
factors involved in mediating the inflammatory response to this infection and their …

Interferons (IFNs) are the key components of innate immunity and are crucial for host
defense against viral infections. Here, we report a novel role of interleukin-17A (IL-17A) in …

Innate immunity provides immediate defense against viral infection. Influenza A virus (IAV) is
able to get past the first line of defense. Elucidation of the molecular interaction between …

IFN-λ is a cytokine expressed in epithelial tissues and plays a central role in antiviral
mucosal immune response. The expression of IFN-λ in the airway is impaired in chronic …