High degree of genetic polymorphism in apolipoprotein (a) associated with plasma lipoprotein (a) levels in Japanese and Chinese populations

S Kikuchi, A Nakagawa, K Kobayashi, L Li, H Yanagi… - Human genetics, 1993 - Springer
We have developed a sensitve, high-resolution method for the analysis of the apolipoprotein
(a)[apo (a)] isoforms using sodium dodecyl sulfate (SDS)-agarose/gradient polyacrylamide …

Effects of the apolipoprotein (a) size polymorphism on the lipoprotein (a) concentration in 7 ethnic groups

C Sandholzer, DM Hallman, N Saha, G Sigurdsson… - Human genetics, 1991 - Springer
Summary Apolipoprotein (a)[apo (a)] exhibits a genetic size polymorphism explaining about
40% of the variability in lipoprotein (a)[Lp (a)] concentration in Tyroleans. Lp (a) …

Studies on apolipoprotein (a) phenotypes. Part 1. Phenotype frequencies in a healthy Japanese population

A Abe, A Noma - Atherosclerosis, 1992 - Elsevier
The frequency distribution for serum lipoprotein (a)(Lp (a)) concentrations in healthy
Japanese was highly skewed, with a mean±SD of 14.6±13.6 mg/dl and a median of 11.0 …

Hypervariable polymorphism of APO (a) in blacks and whites as reflected by phenotyping

MI Kamboh, CM Svitko, ER Williams, RE Ferrell… - Chemistry and physics …, 1994 - Elsevier
Genetic polymorphism at the apolipoprotein (a) structural locus was investigated in 203
American blacks using a high-resolution SDS-agarose electrophoresis method followed by …

Effects of apolipoprotein a gene polymorphisms on lipoprotein (a) concentrations in Japanese

HY Park, T Nabika, Y Notsu… - Clinical and …, 1999 - Wiley Online Library
1. Elevated plasma lipoprotein (a)(Lp (a)) concentrations have been correlated with an
increased risk of premature cardiovascular disease. The plasma Lp (a) concentration is …

Apolipoprotein [a] genotype influences isoform dominance pattern differently in African Americans and Caucasians

J Rubin, F Paultre, CH Tuck, S Holleran, RG Reed… - Journal of lipid …, 2002 - ASBMB
Abstract Plasma lipoprotein [a](Lp [a]) concentrations are inversely associated with, and
largely determined by, apolipoprotein [a](apo [a]) gene size, a highly polymorphic trait. We …

Expressed hypervariable polymorphism of apolipoprotein (a).

MI Kamboh, RE Ferrell, BA Kottke - American journal of human …, 1991 - ncbi.nlm.nih.gov
Elevated plasma lipoprotein (a)(LP (a] levels are an independent predictor of the
development of premature atherosclerosis in humans. The LP (a) particle consists of two …

Contribution of the apo [a] phenotype to plasma Lp [a] concentrations shows considerable ethnic variation.

M Helmhold, J Bigge, R Muche, J Mainoo, J Thiery… - Journal of lipid …, 1991 - Elsevier
Apolipoprotein [a] polymorphism has been investigated by sodium dodecyl sulfate
polyacrylamide (5.37%) gel electrophoresis and immunoblotting using a standardized …

The apolipoprotein (a) gene: a transcribed hypervariable locus controlling plasma lipoprotein (a) concentration

HG Kraft, S Köchl, HJ Menzel, C Sandholzer… - Human genetics, 1992 - Springer
Abstract Lipoprotein (a)[Lp (a)] is a quantitative trait in human plasma. Lp (a) consists of a
low-density lipoprotein and the plasminogen-related apolipoprotein (a)[apo (a)]. The apo (a) …

Identification of 34 apolipoprotein (a) isoforms: differential expression of apolipoprotein (a) alleles between American blacks and whites

SM Marcovina, ZH Zhang, VP Gaur, JJ Albers - … and biophysical research …, 1993 - Elsevier
A total of 34 different apo (a) isoforms was identified in a population sample of 806 American
Whites and 701 American Blacks by a high resolution SDS-agarose gel electrophoretic …