Update on Digoxin Therapy in Congestive Heart Failure | AAFP Advertisement search close
brand logo SHOWKAT A. HAJI, MD, AND ASSAD MOVAHED, MD Am Fam Physician. 2000;62(2):409-416 …

After 200 years of use, digitalis still appears to have a place in our armamentarium for heart
failure and atrial fibrillation despite the proven survival benefits with ACE inhibitors and β …

Digoxin therapy has long been used to treat heart failure; however, its effectiveness was not
completely known until recently. Results of the Digitalis Investigation Group trial showed that …

The recently reported Digitalis Investigation Group (DIG) study has shown that digoxin has
no demonstrable effect on survival in heart failure, but may be useful to ameliorate morbidity …

Background—About half of the 5 million heart failure patients in the United States have
diastolic heart failure (clinical heart failure with normal or near-normal ejection fraction) …

The use of digoxin in the therapy of systolic heart failure and certain supraventricular
tachycardias is controversial. This review of the art and science of digoxin presents …

Because of conflicting results from studies examining the usefulness of digoxin in congestive
heart failure (CHF) patients in sinus rhythm, a cross-over trial was conducted in which 20 …

Controversy continues concerning the use of digoxin as a positive inotropic agent in the
treatment of heart failure in patients in sinus rhythm. Digoxin is properly used to control the …

Digitalis glycosides exert a positive inotropic effect, ie an increase in myocardial contractility
associated with a prolongation of relaxation period, and glycosides lower the heart rate …

The view that digitalis clinically benefits patients with heart failure and sinus rhythm lacks
support from a well-controlled study. Using a randomized, double-blind, crossover protocol …