The alternative splicing of intersectin 1 regulated by PTBP1 promotes human glioma progression
C Lan, H Zhang, K Wang, X Liu, Y Zhao, Z Guo… - Cell Death & …, 2022 - nature.com
Abstract Intersectin 1 (ITSN1) contains two isoforms: ITSN1-S and ITSN1-L, which are highly
regulated by alternative splicing. Our previous results showed that the two isoforms of ITSN1 …
regulated by alternative splicing. Our previous results showed that the two isoforms of ITSN1 …
Alternative splicing-derived intersectin1-L and intersectin1-S exert opposite function in glioma progression
Y Shao, W Chong, X Liu, Y Xu, H Zhang, Q Xu… - Cell death & …, 2019 - nature.com
Abstract Intersectin1 (ITSN1) contains two isoforms: ITSN1-S and ITSN1-L, which is highly
regulated by alternative splicing. However, the alteration of alternative splicing and its …
regulated by alternative splicing. However, the alteration of alternative splicing and its …
Intersectin1‐s, A multidomain adapter protein, Is essential for malignant glioma proliferation
F Gu, H Zhang, F Qin, X Liu, W Li, L Fu, G Ying, B Li… - Glia, 2015 - Wiley Online Library
Glioblastomas, the most aggressive form of primary brain tumors with a tendency to invade
surrounding healthy brain tissues, remains an incurable disease. Intersectin (ITSN) is a …
surrounding healthy brain tissues, remains an incurable disease. Intersectin (ITSN) is a …
Reduction of intersectin1-s induced apoptosis of human glioblastoma cells
Y Ma, B Wang, W Li, G Ying, L Fu, R Niu, F Gu - Brain research, 2010 - Elsevier
Malignant gliomas have a high proliferation ability and high tendency to invade diffusely into
surrounding healthy brain tissues, thereby precluding their successful surgical removal …
surrounding healthy brain tissues, thereby precluding their successful surgical removal …
Intersectin 1 is required for neuroblastoma tumorigenesis
A Russo, JP O'Bryan - Oncogene, 2012 - nature.com
Abstract Intersectin 1 (ITSN1) is a scaffold protein that regulates diverse cellular pathways,
including endocytosis and several signal transduction pathways, including …
including endocytosis and several signal transduction pathways, including …
Intersectin1‐s is involved in migration and invasion of human glioma cells
Y Ma, B Wang, W Li, X Liu, J Wang… - Journal of …, 2011 - Wiley Online Library
Malignant gliomas have a tendency to invade diffusely into surrounding healthy brain
tissues, thereby precluding their successful surgical removal. Intersectin1 (ITSN1) as a …
tissues, thereby precluding their successful surgical removal. Intersectin1 (ITSN1) as a …
Expression analysis of human intersectin 2 gene (ITSN2) minor splice variants showing differential expression in normal human brain
M Seifert, C Ampofo, Y Mehraein… - Oncology …, 2007 - spandidos-publications.com
Human intersectins 1 and 2 (ITSN1 and ITSN2) are conserved proteins involved in clathrin-
mediated endocytosis. In both, two major splice variants, the so-called long and short …
mediated endocytosis. In both, two major splice variants, the so-called long and short …
Intersectin—many facets of a scaffold protein
M Mintoo, V Rajagopalan… - Biochemical Society …, 2024 - portlandpress.com
Intersectin (ITSN) is a multi-domain scaffold protein with a diverse array of functions
including regulation of endocytosis, vesicle transport, and activation of various signal …
including regulation of endocytosis, vesicle transport, and activation of various signal …
Emerging roles for intersectin (ITSN) in regulating signaling and disease pathways
MP Hunter, A Russo, JP O'Bryan - International journal of molecular …, 2013 - mdpi.com
Intersectins (ITSNs) represent a family of multi-domain adaptor proteins that regulate
endocytosis and cell signaling. ITSN genes are highly conserved and present in all …
endocytosis and cell signaling. ITSN genes are highly conserved and present in all …
[HTML][HTML] Intersectin scaffold proteins and their role in cell signaling and endocytosis
E Herrero-Garcia, JP O'Bryan - … et Biophysica Acta (BBA)-Molecular Cell …, 2017 - Elsevier
Intersectins (ITSNs) are a family of multi-domain proteins involved in regulation of diverse
cellular pathways. These scaffold proteins are well known for regulating endocytosis but …
cellular pathways. These scaffold proteins are well known for regulating endocytosis but …