β-Adrenoceptor antagonists in elderly patients with chronic heart failure: therapeutic potential of third-generation agents

AJS Coats - Drugs & aging, 2006 - Springer
Chronic heart failure (CHF) is a common and disabling condition with an incidence and
prevalence that increase sharply with age. The median age of presentation of new heart …

β-Adrenoceptor antagonists in elderly patients with heart failure: a critical review of their efficacy and tolerability

D Dobre, FM Haaijer-Ruskamp, AA Voors… - Drugs & aging, 2007 - Springer
Heart failure (HF) is a major public health problem among the elderly. The syndrome of HF
may arise in the presence of either a depressed or apparently normal left-ventricular ejection …

Beta-blocker therapy in heart failure in the elderly

M Fu - International journal of cardiology, 2008 - Elsevier
Chronic heart failure (CHF) is a common and disabling condition with morbidity and mortality
that increase dramatically with advancing age. There is some evidence available about beta …

Clinical and economic aspects of the use of nebivolol in the treatment of elderly patients with heart failure

D Del Sindaco, MD Tinti, L Monzo… - Clinical interventions in …, 2010 - Taylor & Francis
Heart failure is a common and disabling condition with morbidity and mortality that increase
dramatically with advancing age. Large observational studies, retrospective subgroup …

Heart failure therapy in the elderly: Where are we? What are we doing?

M Fu - International Journal of Cardiology, 2008 - internationaljournalofcardiology.com
Chronic heart failure accompanied by higher comorbidity and mortality is increasing in line
with advancing age. Previous landmark randomised clinical trials were mostly conducted in …

Optimising the use of β-blockers in older patients with heart failure

A Owen - Drugs & aging, 2002 - Springer
Heart failure is predominantly a disease of the older person with half of all patients with the
condition aged> 75 years. Diuretics are the first-line symptomatic treatment for heart failure …

β‐adrenoceptor blockers in chronic heart failure—a review

H Krum - British journal of clinical pharmacology, 1997 - Wiley Online Library
There are now considerable clinical trial data to support the use of β‐adrenoceptor blockers
in patients with chronic heart failure due to systolic left ventricular dysfunction. Increases in …

Study of the Effects of Nebivolol Intervention on Outcomes and Rehospitalisation in Seniors with Heart Failure (SENIORS).: Rationale and design

MC Shibata, MD Flather, M Böhm, J Borbola… - International journal of …, 2002 - Elsevier
Study of the Effects of Nebivolol Intervention on Outcomes and Rehospitalisation in Seniors
with Heart Failure (SENIORS).: Rationale and design - ScienceDirect Skip to main contentSkip …

Tolerability and dose-related effects of nebivolol in elderly patients with heart failure: data from the Study of the Effects of Nebivolol Intervention on Outcomes and …

D Dobre, DJ van Veldhuisen, G Mordenti, M Vintila… - American heart …, 2007 - Elsevier
BACKGROUND: The SENIORS trial showed that nebivolol reduced the risk of death or
cardiovascular (CV) hospitalization in elderly patients with heart failure (HF). We aimed to …

β-Blockade with nebivolol for prevention of acute ischaemic events in elderly patients with heart failure

G Ambrosio, MD Flather, M Böhm, A Cohen-Solal… - Heart, 2011 - heart.bmj.com
Objectives This subanalysis of the Study of the Effects of Nebivolol Intervention on Outcomes
and Hospitalisation in Seniors with Heart Failure (SENIORS) investigates whether treatment …