Understanding the nuances of AmpC β-lactamase–mediated resistance can be challenging,
even for the infectious diseases specialist. AmpC resistance can be classified into 3 …

Background AmpC β-lactamases are encoded on the chromosomes of certain
Enterobacterales and lead to clinical resistance to various β-lactams in case of high-level …

AmpC β-lactamases are clinically important cephalosporinases encoded on the
chromosomes of many of the Enterobacteriaceae and a few other organisms, where they …

AmpC β-lactamases have been a target of study since the late 1970s. Most of these
enzymes are cephalosporinases but are capable of hydrolysing all β-lactams to some …

ABSTRACT Enterobacter spp., Serratia marcescens, Citrobacter freundii, and Morganella
morganii are characterized by chromosomally encoded AmpC β-lactamases and possess …

Some bacteria that possess chromosomally determined AmpC β-lactamases may express
these enzymes at a high level following exposure to β-lactams, either by induction or …

Background Enterobacterales are among the most common causes of bacterial infections in
the community and among hospitalized patients, and multidrug-resistant (MDR) strains have …

Two mechanisms account for AmpC activity in Escherichia coli, namely, mutations in the
ampC promoter and attenuator regions resulting in ampC overexpression and acquisition of …

Although plasmid-mediated AmpC β-lactamases were first reported in the late 1980s, many
infectious disease personnel remain unaware of their clinical importance. These enzymes …

The ampC and ampR genes of Enterobacter cloacae GN7471 were cloned into pMW218 to
yield pKU403. Four mutant plasmids derived from pKU403 (pKU404, pKU405, pKU406, and …