The microbial basis of impaired wound healing: differential roles for pathogens,“bystanders”, and strain-level diversification in clinical outcomes
Chronic, non-healing wounds are a major complication of diabetes associated with high
morbidity and health care expenditures estimated at $9-13 billion annually in the US …
morbidity and health care expenditures estimated at $9-13 billion annually in the US …
Strain-and species-level variation in the microbiome of diabetic wounds is associated with clinical outcomes and therapeutic efficacy
Chronic wounds are a major complication of diabetes associated with high morbidity and
health care expenditures. To investigate the role of colonizing microbiota in diabetic wound …
health care expenditures. To investigate the role of colonizing microbiota in diabetic wound …
Redefining the chronic-wound microbiome: fungal communities are prevalent, dynamic, and associated with delayed healing
L Kalan, M Loesche, BP Hodkinson, K Heilmann… - MBio, 2016 - Am Soc Microbiol
Chronic nonhealing wounds have been heralded as a silent epidemic, causing significant
morbidity and mortality especially in elderly, diabetic, and obese populations. Polymicrobial …
morbidity and mortality especially in elderly, diabetic, and obese populations. Polymicrobial …
The dynamic wound microbiome
Abstract Background Diabetic foot ulcers (DFUs) account for the majority of all limb
amputations and hospitalizations due to diabetes complications. With 30 million cases of …
amputations and hospitalizations due to diabetes complications. With 30 million cases of …
The wound microbiome
The wound microbiome consists of living microbial communities (“microbiota”) that interact
with each other and their surroundings in the injured tissue. The role of the wound …
with each other and their surroundings in the injured tissue. The role of the wound …
[HTML][HTML] Microbiota of chronic diabetic wounds: ecology, impact, and potential for innovative treatment strategies
World Health Organization considered diabetes as one of the 20th century epidemics,
estimating that over 10% of the world population is diabetic or at high risk. Self-assessment …
estimating that over 10% of the world population is diabetic or at high risk. Self-assessment …
Examining diabetic heel ulcers through an ecological lens: microbial community dynamics associated with healing and infection
TJ Sloan, JC Turton, J Tyson… - Journal of medical …, 2019 - microbiologyresearch.org
Purpose. While some micro-organisms, such as Staphylococcus aureus, are clearly
implicated in causing tissue damage in diabetic foot ulcers (DFUs), our knowledge of the …
implicated in causing tissue damage in diabetic foot ulcers (DFUs), our knowledge of the …
The neuropathic diabetic foot ulcer microbiome is associated with clinical factors
Nonhealing diabetic foot ulcers (DFUs) are a common and costly complication of diabetes.
Microbial burden, or “bioburden,” is believed to underlie delayed healing, although little is …
Microbial burden, or “bioburden,” is believed to underlie delayed healing, although little is …
The role of the microbiome in nonhealing diabetic wounds
LR Kalan, MB Brennan - Annals of the New York Academy of …, 2019 - Wiley Online Library
Wound healing is a highly coordinated and complex process, and there can be devastating
consequences if it is interrupted. It is believed that, in combination with host factors …
consequences if it is interrupted. It is believed that, in combination with host factors …
Bad “staph” in the wound environment of diabetic foot ulcers
AS MacLeod - Cell Host & Microbe, 2019 - cell.com
Diabetic foot ulcers (DFUs) are a leading cause of high morbidity among diabetic patients. In
this issue of Cell Host & Microbe, Kalan et al.(2019) examine the microbial bio-burden of …
this issue of Cell Host & Microbe, Kalan et al.(2019) examine the microbial bio-burden of …
相关搜索
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- species level diabetic wounds
- clinical outcomes therapeutic efficacy
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- clinical outcomes species level
- clinical outcomes variation in the microbiome