Efficacy and safety of bempedoic acid in patients with hypercholesterolemia: a systematic review and meta-analysis of randomized controlled trials

L Dai, Y Zuo, Q You, H Zeng… - European journal of …, 2021 - academic.oup.com
Aim Bempedoic acid is a novel oral drug, which has been increasingly researched to play
an important role in the treatment of hypercholesterolemia recently. However, results from …

Efficacy and safety of bempedoic acid for the treatment of hypercholesterolemia: a systematic review and meta-analysis

AFG Cicero, F Fogacci, AV Hernandez, M Banach… - PLoS …, 2020 - journals.plos.org
Background Bempedoic acid is a first-in-class lipid-lowering drug recommended by
guidelines for the treatment of hypercholesterolemia. Our objective was to estimate its …

Efficacy and safety of bempedoic acid in patients with hypercholesterolemia: systematic review and meta‐analysis of randomized controlled trials

A Di Minno, R Lupoli, I Calcaterra… - Journal of the …, 2020 - Am Heart Assoc
Background Bempedoic acid (BA) is a novel lipid‐lowering drug. We performed a systematic
review and meta‐analysis on efficacy and safety of BA compared with standard treatment in …

Cardiovascular events in patients treated with bempedoic acid vs. placebo: systematic review and meta-analysis

D Mutschlechner, M Tscharre, K Huber… - European Heart …, 2023 - academic.oup.com
Aims Reduction of low-density lipoprotein cholesterol (LDL-C) decreases cardiovascular
mortality and morbidity. Bempedoic acid represents a promising novel lipid-modifying agent …

Efficacy and safety of bempedoic acid alone or combining with other lipid-lowering therapies in hypercholesterolemic patients: a meta-analysis of randomized …

X Zhao, X Ma, X Luo, Z Shi, Z Deng, Y Jin… - BMC Pharmacology and …, 2020 - Springer
Background Bempedoic acid is a new drug that reduces cholesterol synthesis via inhibiting
ATP citrate lyase. It remains unclear whether the combination of bempedoic acid and other …

Efficacy and safety of bempedoic acid lipid-lowering therapy: a systematic review and meta-analysis of randomized controlled trials

S Venkatraman, S Das, M Eerike, JJ Cherian… - European Journal of …, 2023 - Springer
Aim This systematic review and meta-analysis was conducted to synthesize the efficacy and
safety of bempedoic acid in patients requiring lipid-lowering therapy. Methods PubMed …

Association of bempedoic acid administration with atherogenic lipid levels in phase 3 randomized clinical trials of patients with hypercholesterolemia

M Banach, PB Duell, AM Gotto, U Laufs… - JAMA …, 2020 - jamanetwork.com
Importance Additional lipid-lowering therapy options are needed for patients who cannot
achieve sufficient decreases in low-density lipoprotein cholesterol (LDL-C) levels using …

Bempedoic acid: new evidence and recommendations on use

K Paponja, I Pećin, Ž Reiner… - Current Opinion in …, 2024 - journals.lww.com
Bempedoic acid has proven beneficial for further reduction of LDL cholesterol for targeted
groups of patients. It is not only efficient but also a well tolerated, affordable, and available …

[HTML][HTML] Efficacy and safety of bempedoic acid in patients with and without metabolic syndrome: Pooled analysis of data from four phase 3 clinical trials

MD Shapiro, PR Taub, MJ Louie, L Lei, CM Ballantyne - Atherosclerosis, 2023 - Elsevier
Background and aims Bempedoic acid significantly lowers low-density lipoprotein
cholesterol (LDL-C) in patients with hypercholesterolemia but its effects in patients with …

Updated clinical evidence and place in therapy of bempedoic acid for hypercholesterolemia: ANMCO position paper

F Colivicchi, SA Di Fusco, P Scicchitano… - Journal of …, 2021 - journals.lww.com
The central role of high low-density lipoprotein cholesterol levels in atherosclerotic
cardiovascular disease has led to research focused on lipid-lowering agents for …