In 2008, the National Institute of Mental Health (NIMH) included in its new Strategic Plan the
following aim:“Develop, for research purposes, new ways of classifying mental disorders …

Autism spectrum disorder (ASD) has phenotypically and genetically heterogeneous
characteristics. A simulation study demonstrated that attempts to categorize patients with a …

Individuals affected by autism spectrum conditions (ASC) are considerably heterogeneous.
Novel approaches are needed to parse this heterogeneity to enhance precision in clinical …

Autism spectrum disorder (ASD) is a developmental disorder that impacts more than 1.6% of
children aged 8 across the United States. It is characterized by impairments in social …

Background ADHD is diagnosed and treated more often in males than in females. Research
on gender differences suggests that girls may be consistently underidentified and …

Abstract Machine learning approaches have been widely used for the identification of
neuropathology from neuroimaging data. However, these approaches require large samples …

Objective The aims of this study were to elucidate the influence of common genetic variants
on childhood attention-deficit/hyperactivity disorder (ADHD) symptoms, to identify genetic …

Background Relying on diagnostic categories of neuropsychiatric illness obscures the
complexity of these disorders. Capturing multiple dimensional measures of neuropathology …

The traditional view that mental disorders are distinct, categorical disorders has been
challenged by evidence that disorders are highly comorbid and exist on a continuum (eg …

Background: There is evidence suggesting neuropsychiatric disorders share genomic,
cognitive and clinical features. Here, we ask if autism-spectrum disorders (ASD), attention …