Sexual Isolation in Acinetobacter baylyi Is Locus-Specific and Varies 10,000-Fold Over the Genome

JL Ray, K Harms, OG Wikmark, I Starikova… - Genetics, 2009 - academic.oup.com
Naturally transformable bacteria acquire chromosomal DNA from related species at lower
frequencies than from cognate DNA sources. To determine how genome location affects …

[HTML][HTML] Costs and benefits of natural transformation in Acinetobacter baylyi

N Hülter, V Sørum, K Borch-Pedersen, MM Liljegren… - BMC microbiology, 2017 - Springer
Background Natural transformation enables acquisition of adaptive traits and drives genome
evolution in prokaryotes. Yet, the selective forces responsible for the evolution and …

Testing for the fitness benefits of natural transformation during community-embedded evolution

M Winter, K Harms, PJ Johnsen, A Buckling… - …, 2023 - microbiologyresearch.org
Natural transformation is a process where bacteria actively take up DNA from the
environment and recombine it into their genome or reconvert it into extra-chromosomal …

Natural transformation as a tool in Acinetobacter baylyi: Streamlined engineering and mutational analysis

SR Bedore, EL Neidle, I Pardo, J Luo, AC Baugh… - Methods in …, 2023 - Elsevier
Natural transformation and homologous recombination in a soil bacterium, Acinetobacter
baylyi ADP1, occur with exceptionally high efficiency. These genetic features can be …

Restriction–methylation systems regulate transformation in Acinetobacter baumannii

A Soler-Bistué - Trends in Microbiology, 2023 - cell.com
Antimicrobial resistance in Acinetobacter baumannii is a major concern. Natural
transformation remains understudied as a horizontal gene transfer (HGT) mechanism for the …

Double illegitimate recombination events integrate DNA segments through two different mechanisms during natural transformation of Acinetobacter baylyi

N Hülter, W Wackernagel - Molecular microbiology, 2008 - Wiley Online Library
Acquisition of foreign DNA by horizontal gene transfer is seen as a major source of genetic
diversity in prokaryotes. However, strongly divergent DNA is not genomically integrated by …

Rapid Evolution of Diminished Transformability in Acinetobacter baylyi

JM Bacher, D Metzgar… - Journal of bacteriology, 2006 - Am Soc Microbiol
The reason for genetic exchange remains a crucial question in evolutionary biology.
Acinetobacter baylyi strain ADP1 is a highly competent and recombinogenic bacterium. We …

DNA modifications impact natural transformation of Acinetobacter baumannii

N Vesel, C Iseli, N Guex, A Lemopoulos… - Nucleic Acids …, 2023 - academic.oup.com
Acinetobacter baumannii is a dangerous nosocomial pathogen, especially due to its ability
to rapidly acquire new genetic traits, including antibiotic resistance genes (ARG). In A …

Reduced mutation rate and increased transformability of transposon-free Acinetobacter baylyi ADP1-ISx

GA Suárez, BA Renda, A Dasgupta… - Applied and …, 2017 - Am Soc Microbiol
The genomes of most bacteria contain mobile DNA elements that can contribute to
undesirable genetic instability in engineered cells. In particular, transposable insertion …

Growth phase-specific evolutionary benefits of natural transformation in Acinetobacter baylyi

ALG Utnes, V Sørum, N Hülter, R Primicerio… - The ISME …, 2015 - academic.oup.com
Natural transformation in bacteria facilitates the uptake and genomic integration of
exogenous DNA. This allows horizontal exchange of adaptive traits not easily achieved by …