Fetal, maternal, and placental sources of serotonin and new implications for developmental programming of the brain
In addition to its role in neurotransmission, embryonic serotonin (5-HT) has been implicated
in the regulation of neurodevelopmental processes. For example, we recently showed that a …
in the regulation of neurodevelopmental processes. For example, we recently showed that a …
Postnatal changes in serotonin1 receptors following prenatal alterations in serotonin levels: further evidence for functional fetal serotonin1 receptors
PM Whitaker-Azmitia, JM Lauder, A Shemmer… - Developmental Brain …, 1987 - Elsevier
Recent work by ourselves and others has indicated that serotonin (5-HT) acts as a regulator
of neuronal growth in fetal tissue, probably through an action on the high affinity 5-HT …
of neuronal growth in fetal tissue, probably through an action on the high affinity 5-HT …
A transient placental source of serotonin for the fetal forebrain
Abstract Serotonin (5-hydroxytryptamine or 5-HT) is thought to regulate neurodevelopmental
processes through maternal–fetal interactions that have long-term mental health …
processes through maternal–fetal interactions that have long-term mental health …
Maternal serotonin is crucial for murine embryonic development
F Côté, C Fligny, E Bayard… - Proceedings of the …, 2007 - National Acad Sciences
The early appearance of serotonin and its receptors during prenatal development, together
with the many effects serotonin exerts during CNS morphogenesis, strongly suggest that …
with the many effects serotonin exerts during CNS morphogenesis, strongly suggest that …
[HTML][HTML] Placental serotonin: implications for the developmental effects of SSRIs and maternal depression
JC Velasquez, N Goeden, A Bonnin - Frontiers in cellular …, 2013 - frontiersin.org
In addition to its role in the pathophysiology of numerous psychiatric disorders, increasing
evidence points to serotonin (5-HT) as a crucial molecule for the modulation of …
evidence points to serotonin (5-HT) as a crucial molecule for the modulation of …
Gestational factors throughout fetal neurodevelopment: the serotonin link
SI Hanswijk, M Spoelder, L Shan, MMM Verheij… - International journal of …, 2020 - mdpi.com
Serotonin (5-HT) is a critical player in brain development and neuropsychiatric disorders.
Fetal 5-HT levels can be influenced by several gestational factors, such as maternal …
Fetal 5-HT levels can be influenced by several gestational factors, such as maternal …
Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development
Serotonin (5-HT) is implicated in several aspects of brain development, yet the ontogenetic
expression patterns of 5-HT receptors responsible for transducing specific effects have …
expression patterns of 5-HT receptors responsible for transducing specific effects have …
[HTML][HTML] Refining the role of 5-HT in postnatal development of brain circuits
Changing serotonin (5-hydroxytryptamine, 5-HT) brain levels during critical periods in
development has long-lasting effects on brain function, particularly on later …
development has long-lasting effects on brain function, particularly on later …
Maternal inflammation disrupts fetal neurodevelopment via increased placental output of serotonin to the fetal brain
N Goeden, J Velasquez, KA Arnold… - Journal of …, 2016 - Soc Neuroscience
Maternal inflammation during pregnancy affects placental function and is associated with
increased risk of neurodevelopmental disorders in the offspring. The molecular mechanisms …
increased risk of neurodevelopmental disorders in the offspring. The molecular mechanisms …
Expression of serotonin transporter protein in developing rat brain
FC Zhou, Y Sari, JK Zhang - Developmental Brain Research, 2000 - Elsevier
Serotonin transporter (5-HTT), a transmembrane protein, has been shown in adult brain to
be distributed not only on synaptic terminals but to a great extent on axons as well. Here we …
be distributed not only on synaptic terminals but to a great extent on axons as well. Here we …