Nanotherapy for posterior eye diseases

IP Kaur, S Kakkar - Journal of Controlled Release, 2014 - Elsevier
It is assumed that more than 50% of the most enfeebling ocular diseases have their origin in
the posterior segment. Furthermore, most of these diseases lead to partial or complete …

Therapies based on nanoparticles for eye drug delivery

A Meza-Rios, J Navarro-Partida… - Ophthalmology and …, 2020 - Springer
Eye drug delivery, particularly to the retina, is a technical hurdle that needs to be solved and
represents an ongoing current important medical field. Posterior segment eye diseases are …

A review of nanocarrier-mediated drug delivery systems for posterior segment eye disease: Challenges analysis and recent advances

R Wang, Y Gao, A Liu, G Zhai - Journal of drug targeting, 2021 - Taylor & Francis
Posterior segment eye disease is a leading cause of irreversible vision impairment and
blindness. As the unique organ for vision, eyes are protected by various protective barriers …

Recent advance of nanoparticle-based topical drug delivery to the posterior segment of the eye

Y Wang, X Xu, Y Gu, Y Cheng, F Cao - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Considering that the number of patients afflicted by posterior eye diseases is
increasing, effective drug delivery is currently in high clinical demand. Topical administration …

Recent perspectives in ocular drug delivery

R Gaudana, J Jwala, SHS Boddu, AK Mitra - Pharmaceutical research, 2009 - Springer
Anatomy and physiology of the eye makes it a highly protected organ. Designing an effective
therapy for ocular diseases, especially for the posterior segment, has been considered as a …

Nano-based eye drop: Topical and noninvasive therapy for ocular diseases

C Wang, Y Pang - Advanced drug delivery reviews, 2023 - Elsevier
Eye drops are the most accessible therapy for ocular diseases, while inevitably suffering
from their lower bioavailability which highly restricts the treatment efficacy. The introduction …

Ocular drug delivery: present innovations and future challenges

V Gote, S Sikder, J Sicotte, D Pal - Journal of Pharmacology and …, 2019 - ASPET
Ocular drug delivery has always been a challenge for ophthalmologists and drug-delivery
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …

[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

AL Onugwu, CS Nwagwu, OS Onugwu… - Journal of Controlled …, 2023 - Elsevier
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …

Nano-based drug delivery system: recent strategies for the treatment of ocular disease and future perspective

Z Qamar, FF Qizilbash, MK Iqubal, A Ali… - Recent Patents on …, 2019 - ingentaconnect.com
The structure of the eye is very complex in nature which makes it a challenging task for
pharmaceutical researchers to deliver the drug at the desired sites via different routes of …

Trends in formulation approaches for sustained drug delivery to the posterior segment of the eye

A Biswas, AD Choudhury, AC Bisen, S Agrawal… - AAPS …, 2023 - Springer
The eye, an intricate organ comprising physical and physiological barriers, poses a
significant challenge for ophthalmic physicians seeking to treat serious ocular diseases …