Assembly of upconversion nanophotosensitizer in vivo to achieve scatheless real-time imaging and selective photodynamic therapy

Y Feng, Y Wu, J Zuo, L Tu, I Que, Y Chang, LJ Cruz… - Biomaterials, 2019 - Elsevier
A perfect “off” to “on” switch of the therapeutic function is very important to minimize the
phototoxicity of nanoplatforms assisted imaging-guided photodynamic therapy (PDT) of …

In vivo 808 nm image-guided photodynamic therapy based on an upconversion theranostic nanoplatform

X Liu, I Que, X Kong, Y Zhang, L Tu, Y Chang, TT Wang… - Nanoscale, 2015 - pubs.rsc.org
A new strategy for efficient in vivo image-guided photodynamic therapy (PDT) has been
demonstrated utilizing a ligand-exchange constructed upconversion-C60 …

Optical imaging and pH-awakening therapy of deep tissue cancer based on specific upconversion nanophotosensitizers

Y Feng, H Chen, Y Wu, I Que, F Tamburini, F Baldazzi… - Biomaterials, 2020 - Elsevier
Side effect is one of the main factors affecting the success of cancer therapies in clinic.
Patients treated with photodynamic therapy (PDT) suffer mainly from the phototoxicity due to …

Development of a novel anti-tumor theranostic platform: a near-infrared molecular upconversion sensitizer for deep-seated cancer photodynamic therapy

R Tian, W Sun, M Li, S Long, M Li, J Fan, L Guo… - Chemical …, 2019 - pubs.rsc.org
Upconversion-based photon-initiated therapeutic modalities, photodynamic therapy (PDT) in
particular, have shown significant clinical potential in deep-seated tumor treatment …

Near infrared light sensitive ultraviolet–blue nanophotoswitch for imaging-guided “off–on” therapy

J Zuo, L Tu, Q Li, Y Feng, I Que, Y Zhang, X Liu… - ACS …, 2018 - ACS Publications
Photoswitchable materials are important in broad applications. Recently appeared inorganic
photoswitchable upconversion nanoparticles (PUCNPs) become a competitive candidate to …

Facile assembly of functional upconversion nanoparticles for targeted cancer imaging and photodynamic therapy

L Liang, A Care, R Zhang, Y Lu… - … applied materials & …, 2016 - ACS Publications
The treatment depth of existing photodynamic therapy (PDT) is limited because of the
absorption of visible excitation light in biological tissue. It can be augmented by means of …

Near-infrared light triggered photodynamic therapy in combination with gene therapy using upconversion nanoparticles for effective cancer cell killing

X Wang, K Liu, G Yang, L Cheng, L He, Y Liu, Y Li… - Nanoscale, 2014 - pubs.rsc.org
Upconversion nanoparticles (UCNPs) have drawn much attention in cancer imaging and
therapy in recent years. Herein, we for the first time report the use of UCNPs with carefully …

Near-infrared light induced in vivo photodynamic therapy of cancer based on upconversion nanoparticles

C Wang, H Tao, L Cheng, Z Liu - Biomaterials, 2011 - Elsevier
Upconversion nanoparticles (UCNPs) that emit high-energy photons upon excitation by the
low-energy near-infrared (NIR) light are emerging as new optical nano-probes useful in …

Upconversion nanoparticle-based optogenetic nanosystem for photodynamic therapy and cascade gene therapy

X Song, F Li, F Tian, L Ren, Q Wang, C Jiang, T Yan… - Acta Biomaterialia, 2023 - Elsevier
Most photosensitizer molecules used for the photodynamic therapy (PDT) are chemically-
synthesized organic photosensitizer dyes which show several limitations such as …

Near-infrared upconversion photosensitizer enabling photodynamic production and in situ dynamic monitoring of hydroxyl radical in live mice

T Jia, J Du, J Yang, F Li, X Fang, G Chen - Nano Today, 2023 - Elsevier
Upconversion photodynamic therapy (PDT), utilizing upconversion nanoparticles (UCNPs)
to excite surface-anchored molecular photosensitizers, enables to treat deep-seated tumors …