Therapeutic features and updated clinical trials of mesenchymal stem cell (MSC)-derived exosomes

BC Lee, I Kang, KR Yu - Journal of clinical medicine, 2021 - mdpi.com
Identification of the immunomodulatory and regenerative properties of mesenchymal stem
cells (MSCs) have made them an attractive alternative therapeutic option for diseases with …

New therapeutic approaches of mesenchymal stem cells-derived exosomes

J Janockova, L Slovinska, D Harvanova… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem cells (MSCs) have been demonstrated to have a great potential in the
treatment of several diseases due to their differentiation and immunomodulatory capabilities …

Mesenchymal stem cell-derived exosomes for clinical use

M Mendt, K Rezvani, E Shpall - Bone marrow transplantation, 2019 - nature.com
Mesenchymal stem/stromal cells (MSCs) are commonly used as a source of cellular therapy
due to their strong immunosuppressive and regenerative effects. One of the key …

Exosomes from mesenchymal stem/stromal cells: a new therapeutic paradigm

K Yin, S Wang, RC Zhao - Biomarker research, 2019 - Springer
Mesenchymal stem/stromal cells (MSCs) have been demonstrated to hold great potential for
the treatment of several diseases. Their therapeutic effects are largely mediated by …

Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials

A Lotfy, NM AboQuella, H Wang - Stem Cell Research & Therapy, 2023 - Springer
Mesenchymal stromal/stem cells (MSCs) are widely utilized in cell therapy because of their
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …

Challenges and strategies: scalable and efficient production of mesenchymal stem cells-derived exosomes for cell-free therapy

W Pan, H Chen, A Wang, F Wang, X Zhang - Life sciences, 2023 - Elsevier
Exosomes are small membrane vesicles secreted by most cell types, and widely exist in cell
supernatants and various body fluids. They can transmit numerous bioactive elements, such …

[HTML][HTML] Mesenchymal stem cell-derived exosomes: Toward cell-free therapeutic strategies in regenerative medicine

ZJ Ma, JJ Yang, YB Lu, ZY Liu… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are multipotent stem cells with marked potential for
regenerative medicine because of their strong immunosuppressive and regenerative …

Current knowledge and future perspectives on mesenchymal stem cell-derived exosomes as a new therapeutic agent

HS Joo, JH Suh, HJ Lee, ES Bang, JM Lee - International journal of …, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) are on the cusp of regenerative medicine due to their
differentiation capacity, favorable culture conditions, ability to be manipulated in vitro, and …

Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine

S Nikfarjam, J Rezaie, NM Zolbanin, R Jafari - Journal of translational …, 2020 - Springer
Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …

[HTML][HTML] Mesenchymal stromal/stem cells spheroid culture effect on the therapeutic efficacy of these cells and their exosomes: A new strategy to overcome cell therapy …

A Hazrati, K Malekpour, S Soudi… - Biomedicine & …, 2022 - Elsevier
Cell therapy is one of the new treatment methods in which mesenchymal stem/stromal cell
(MSCs) transplantation is one of the cells widely used in this field. The results of MSCs …