Natural transformation increases the genetic diversity of bacteria, but is costly and must be
strictly controlled. We previously found that deletion of ccpA, a key regulator of carbon …

In this study, we carried out a detailed structural and functional analysis of a Streptococcus
agalactiae (GBS) two‐component system which is orthologous to the CovS/CovR …

As an inhabitant of the human oral cavity, Streptococcus mutans faces frequent
environmental changes. Two-component regulatory systems (TCSs) play a critical role in …

A locus encoding proteins with high homology to the pneumococcal BlpABCHR quorum-
sensing system was identified in Streptococcus thermophilus LMG 18311. The BlpABCHR …

S. mitis is an abundant member of the commensal microbiota of the oral cavity and pharynx,
which has the potential to promote systemic infections. By analyzing a collection of S. mitis …

Bacteria use quorum sensing (QS) to communicate with each other via secreted small
autoinducers produced by individuals. QS allows bacteria to display a unified response that …

Trigger factor is a ribosome-associated peptidyl-prolyl cis/trans isomerase that is highly
conserved in most bacteria. A gene, designated ropA, encoding an apparent trigger factor …

ABSTRACT The RelA, RelP, and RelQ enzymes are responsible for the production of the
alarmone (p) ppGpp in Streptococcus mutans. A strain lacking all three synthetases (Δ …

Recently, high-coverage genome sequence of 57 isolates of Streptococcus mutans, the
primary etiological agent of human dental caries, was completed. The SMU. 1147 gene …

Streptococcus gallolyticus subsp. gallolyticus, a member of the group D streptococci, is
normally found in the bovine rumen and human gut. It is an opportunistic pathogen that was …