Triglyceride-rich lipoproteins and atherosclerotic cardiovascular disease: new insights from epidemiology, genetics, and biology

BG Nordestgaard - Circulation research, 2016 - Am Heart Assoc
Scientific interest in triglyceride-rich lipoproteins has fluctuated over the past many years,
ranging from beliefs that these lipoproteins cause atherosclerotic cardiovascular disease …

[HTML][HTML] Triglycerides and risk of atherosclerotic cardiovascular disease: an update

M Farnier, M Zeller, D Masson, Y Cottin - Archives of cardiovascular …, 2021 - Elsevier
Low-density lipoprotein cholesterol is a well-known causal factor for atherosclerotic
cardiovascular disease, and is the primary target of lipid-lowering therapy. There is …

Triglycerides and heart disease: still a hypothesis?

IJ Goldberg, RH Eckel, R McPherson - … , thrombosis, and vascular …, 2011 - Am Heart Assoc
The purpose of this article is to review the basic and clinical science relating plasma
triglycerides and cardiovascular disease. Although many aspects of the basic physiology of …

[HTML][HTML] Serum triglycerides and atherosclerotic cardiovascular disease: insights from clinical and genetic studies

H Tada, A Nohara, M Kawashiri - Nutrients, 2018 - mdpi.com
Lipoproteins are a major risk factor for atherosclerotic cardiovascular diseases (ASCVD).
Among the lipoproteins, low-density lipoproteins (LDL) have been shown to be causally …

A risk factor for atherosclerosis: triglyceride-rich lipoproteins.

MJ Malloy, JP Kane - Advances in internal medicine, 2001 - europepmc.org
Compelling evidence from meta-analysis of a number of clinical studies on a large
aggregate of patients has established an increased level of triglycerides as an independent …

Genetics and causality of triglyceride-rich lipoproteins in atherosclerotic cardiovascular disease

RS Rosenson, MH Davidson, BJ Hirsh… - Journal of the American …, 2014 - jacc.org
Triglycerides represent 1 component of a heterogeneous pool of triglyceride-rich
lipoproteins (TGRLs). The reliance on triglycerides or TGRLs as cardiovascular disease …

Triglyceride-rich lipoproteins as a causal factor for cardiovascular disease

PP Toth - Vascular health and risk management, 2016 - Taylor & Francis
Approximately 25% of US adults are estimated to have hypertriglyceridemia (triglyceride
[TG] level≥ 150 mg/dL [≥ 1.7 mmol/L]). Elevated TG levels are associated with increased …

Triglycerides and atherogenic lipoproteins: rationale for lipid management

RM Krauss - The American journal of medicine, 1998 - Elsevier
Epidemiologic and clinical studies have demonstrated a relation between plasma
triglyceride levels and risk of coronary artery disease and an amplification of risk with …

[HTML][HTML] Triglycerides and triglyceride-rich lipoproteins in the causal pathway of cardiovascular disease

M Budoff - The American journal of cardiology, 2016 - Elsevier
Epidemiologic and clinical studies suggest that elevated triglyceride levels are a biomarker
of cardiovascular (CV) risk. Consistent with these findings, recent genetic evidence from …

Fasting triglycerides, high-density lipoprotein, and risk of myocardial infarction

JM Gaziano, CH Hennekens, CJ O'Donnell… - Circulation, 1997 - Am Heart Assoc
Background Recent data suggest that triglyceride-rich lipoproteins may play a role in
atherogenesis. However, whether triglycerides, as a marker for these lipoproteins, represent …