[HTML][HTML] Gut microbiota composition is associated with the global DNA methylation pattern in obesity

B Ramos-Molina, L Sánchez-Alcoholado… - Frontiers in …, 2019 - frontiersin.org
Objective: Obesity and obesity-related metabolic diseases are characterized by gut
microbiota and epigenetic alterations. Recent insight has suggested the existence of a …

[HTML][HTML] Crosstalk between Gut Microbiota and Epigenetic Markers in Obesity Development: Relationship between Ruminococcus, BMI, and MACROD2/SEL1L2 …

F Salas-Perez, TS Assmann, O Ramos-Lopez… - Nutrients, 2023 - mdpi.com
Changes in gut microbiota composition and in epigenetic mechanisms have been proposed
to play important roles in energy homeostasis, and the onset and development of obesity …

Gut microbiota as an epigenetic regulator: pilot study based on whole-genome methylation analysis

H Kumar, R Lund, A Laiho, K Lundelin, RE Ley… - MBio, 2014 - Am Soc Microbiol
The core human gut microbiota contributes to the developmental origin of diseases by
modifying metabolic pathways. To evaluate the predominant microbiota as an epigenetic …

[HTML][HTML] The epigenetic connection between the gut microbiome in obesity and diabetes

M Sharma, Y Li, ML Stoll, TO Tollefsbol - Frontiers in genetics, 2020 - frontiersin.org
Metabolic diseases are becoming an alarming health issue due to elevated incidences of
these diseases over the past few decades. Various environmental factors are associated …

Gut microbiota induces DNA methylation via SCFAs predisposing obesity-prone individuals to diabetes

W Guo, Z Zhang, L Li, X Liang, Y Wu, X Wang… - Pharmacological …, 2022 - Elsevier
Obesity-prone (OP) individuals have a significant predisposition to obesity and diabetes.
Previously, we have found that OP individuals, despite being normal in weight and BMI …

[HTML][HTML] Specific gut microbiota features and metabolic markers in postmenopausal women with obesity

LK Brahe, E Le Chatelier, E Prifti, N Pons… - Nutrition & …, 2015 - nature.com
Background: Gut microbial gene richness and specific bacterial species are associated with
metabolic risk markers in humans, but the impact of host physiology and dietary habits on …

[HTML][HTML] Diet, gut microbiota, and obesity: links with host genetics and epigenetics and potential applications

A Cuevas-Sierra, O Ramos-Lopez, JI Riezu-Boj… - Advances in …, 2019 - Elsevier
Diverse evidence suggests that the gut microbiota is involved in the development of obesity
and associated comorbidities. It has been reported that the composition of the gut microbiota …

Distinct differences in gut microbial composition and functional potential from lean to morbidly obese subjects

AS Meijnikman, O Aydin, A Prodan… - Journal of Internal …, 2020 - Wiley Online Library
Introduction The gut microbiome may contribute to the development of obesity. So far, the
extent of microbiome variation in people with obesity has not been determined in large …

Heritable components of the human fecal microbiome are associated with visceral fat

CI Le Roy, M Beaumont, MA Jackson, CJ Steves… - Gut …, 2018 - Taylor & Francis
Obesity and its associated diseases are one of the major causes of death worldwide. The
gut microbiota has been identified to have essential regulatory effects on human metabolism …

[HTML][HTML] DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese …

AB Crujeiras, A Diaz-Lagares, J Sandoval, FI Milagro… - Scientific reports, 2017 - nature.com
The characterization of the epigenetic changes within the obesity-related adipose tissue will
provide new insights to understand this metabolic disorder, but adipose tissue is not easy to …