5-Hydroxytryptamine1A receptor binding activity of bisbenzyltetrahydroisoquinoline alkaloids from Popowia odoardi

LY Chung, WK Soo, MR Mustafa, SH Goh… - Pharmaceutical …, 2009 - Taylor & Francis
A 96-well filtration-based 5-HT1A receptor-radioligand binding assay was optimized and
adapted to carry out a bioassay-guided fractionation of the methanol extract of the bark of …

Isoquinoline Derivatives Isolated from the Fruit of Annona muricata as 5-HTergic 5-HT1A Receptor Agonists in Rats: Unexploited Antidepressive (Lead) Products

JA Hasrat, T De Bruyne, JP De Backer… - Journal of pharmacy …, 1997 - academic.oup.com
The fruit and the leaves of Annona muricata (Annonaceae) are used in traditional medicine
for their tranquillizing and sedative properties. Extracts of the plant have been shown to …

5‐Hydroxytryptamine2A receptor binding activity of compounds from Litsea sessilis

LY Chung, MW Lo, MR Mustafa… - … Journal Devoted to …, 2009 - Wiley Online Library
A 96‐well microplate filtration based 5‐HT2A receptor‐radioligand binding assay was
optimized and adopted to carry out a bioassay‐guided fractionation of the methanol extract …

Alkaloids from Eschscholzia californica and Their Capacity to Inhibit Binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A Receptors in Vitro

S Gafner, BM Dietz, KL McPhail, IM Scott… - Journal of natural …, 2006 - ACS Publications
A 70% ethanol extract of California poppy (Eschscholzia californica) was able to bind to 5-
HT1A and 5-HT7 receptors at 100 μg/mL. The subsequent isolation procedure yielded the …

Screening of medicinal plants from Suriname for 5-HT1A ligands: Bioactive isoquinoline alkaloids from the fruit of Annona muricata

JA Hasrat, L Pieters, JP De Backer, G Vauquelin… - Phytomedicine, 1997 - Elsevier
Plants from Suriname (South-America) and several Annona species, including A. muricata,
A. ckerimolia, A. montana and A. glabra were screened for 5-HT1A receptor binding activity …

Effects of Geissoschizine Methyl Ether, an Indole Alkaloid in Uncaria Hook, a Constituent of Yokukansan, on Human Recombinant Serotonin7 Receptor

T Ueki, A Nishi, S Imamura, H Kanno… - Cellular and molecular …, 2013 - Springer
Abstract Effects of seven alkaloids, geissoschizine methyl ether (GM), hirsutine, hirsuteine,
rhynchophylline, isorhynchophylline, corynoxeine and isocorynoxeine, in Uncaria hook, a …

Partial agonistic effect of yokukansan on human recombinant serotonin 1A receptors expressed in the membranes of Chinese hamster ovary cells

K Terawaki, Y Ikarashi, K Sekiguchi, Y Nakai… - Journal of …, 2010 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Yokukansan (YKS) is a traditional Japanese
medicine consisted of seven medicinal herbs and has been used for treatment of neurosis …

Examining Ayahuasca Constituents at 5-HT2A Receptors in Search of Antidepressant Action

JD Rolquin - 2022 - scholarscompass.vcu.edu
Recently, it has been reported that ligands of the 5-HT 2A receptor can have drastic and fast-
acting efficacy towards a number of different mental health disorders, such as depression …

Yokukansan contains compounds that antagonize the 5-HT3 receptor

Y Nakamura, Y Ishida, M Kondo, S Shimada - Phytomedicine, 2018 - Elsevier
Background We recently focused on alkaloids in Uncaria hook (a constituent of the Kampo
medicine, yokukansan) and identified the pharmacological action of geissoschizine methyl …

Central nervous system receptor activities of some Malaysian plant species

LY Chung, SH Goh, Z Imiyabir - Pharmaceutical biology, 2005 - Taylor & Francis
In this investigation, 185 plant samples representing more than 30 plant families collected
from the Malaysian forests were assessed for their ability to inhibit specific radioligand …