Natural killer cells in HIV-1 infection and therapy

J Mikulak, F Oriolo, E Zaghi, C Di Vito, D Mavilio - Aids, 2017 - journals.lww.com
Natural killer (NK) cells are important effectors of innate immunity playing a key role in the
eradication and clearance of viral infections. Over the recent years, several studies have …

NK cells in HIV infection: paradigm for protection or targets for ambush

AS Fauci, D Mavilio, S Kottilil - Nature Reviews Immunology, 2005 - nature.com
Natural killer cells are a crucial component of the innate immune response to certain
tumours and to various viruses, fungi, parasites and bacteria. HIV has infected more than 60 …

Natural killer cells in HIV-1 infection: dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates

D Mavilio, J Benjamin, M Daucher… - Proceedings of the …, 2003 - National Acad Sciences
Natural killer (NK) cells play a central role in host defense against various pathogens.
Functional defects of NK cells in HIV-1 infection as a direct effect of abnormal expression or …

Dysfunctional natural killer cells, in vivo, are governed by HIV viremia regardless of whether the infected individual is on antiretroviral therapy

E Barker, J Martinson, C Brooks, A Landay, S Deeks - Aids, 2007 - journals.lww.com
Progression to AIDS during HIV-infection is associated with a decrease in the number and
function of natural killer (NK) cells [1–4]. The reduction in NK cells expressing CD56 and …

[HTML][HTML] NK cells in HIV disease

E Scully, G Alter - Current HIV/AIDS Reports, 2016 - Springer
Natural killer (NK) cells play a critical role in viral immunity. In the setting of HIV infection,
epidemiologic and functional evidence support a role for NK cells in both protection from …

Specific phenotypic and functional features of natural killer cells from HIV-infected long-term nonprogressors and HIV controllers

V Vieillard, H Fausther-Bovendo, A Samri… - JAIDS Journal of …, 2010 - journals.lww.com
Background: Recent evidence suggests that natural killer (NK) cells play a crucial role in the
HIV pathogenesis. Long-term nonprogressor (LTNP) and HIV controllers are rare HIV …

High Frequencies of Polyfunctional CD8+ NK Cells in Chronic HIV-1 Infection Are Associated with Slower Disease Progression

F Ahmad, HS Hong, M Jäckel, A Jablonka… - Journal of …, 2014 - Am Soc Microbiol
Natural killer (NK) cells are effector and regulatory innate immune cells and play a critical
role in the first line of defense against various viral infections. Although previous reports …

NK cells in HIV‐1 infection: evidence for their role in the control of HIV‐1 infection

G Alter, M Altfeld - Journal of internal medicine, 2009 - Wiley Online Library
Increasing evidence supports the notion that the innate immune response, and in particular,
natural killer cells play a central role in determining the quality of the host immune response …

Natural killer cell function in patients with acquired immunodeficiency syndrome and related diseases

BG Brenner, A Dascal, RG Margolese… - Journal of Leukocyte …, 1989 - Wiley Online Library
This review describes current knowledge of changes in natural killer (NK) cell function in
acquired immunodeficiency syndrome (AIDS)‐related disorders, vis‐à‐vis associated …

Natural killer cell function is well preserved in asymptomatic human immunodeficiency virus type 2 (HIV-2) infection but similar to that of HIV-1 infection when CD4 T …

SV Nuvor, M van der Sande, S Rowland-Jones… - Journal of …, 2006 - Am Soc Microbiol
Natural killer (NK) cells are potent effectors of natural immunity and their activity prevents
human immunodeficiency virus type 1 (HIV-1) viral entry and viral replication. We sought to …