Colorectal cancer (CRC) is one of the most lethal malignancies worldwide and CRC therapy
remains unsatisfactory. In recent decades, nitric oxide (NO)—a free-radical gas—plus its …

Nitric oxide (NO) is involved in various physiological functions and its role in tumorigenesis
has been well studied. A large majority of human and experimental tumors appear to …

Nitric oxide (NO) is a short-lived, pleiotropic molecule that affects numerous critical functions
in the body. Presently, there are markedly conflicting findings in the literature regarding NO …

In recent years, there has been an increasing interest in understanding the mysterious
functions of nitric oxide (NO) and how this pleiotropic signaling molecule contributes to …

The role of reactive nitrogen species (RNS) in colon carcinogenesis is multifactorial and
affects diverse processes, such as proliferation, apoptosis, differentiation, tumorigenesis …

Nitric oxide (NO) is a pleiotrophic regulator, pivotal to numerous biological processes,
including vasodilation, neurotransmission, and macrophage-mediated immunity. The highly …

Utilizing targeted therapies capable of reducing cancer metastasis, targeting chemoresistant
and self-renewing cancer stem cells, and augmenting the efficacy of systemic …

Nitric oxide (NO) is a signaling molecule with pleiotropic physiological roles in normal cells
and pathophysiological roles in cancer. NO synthetase expression and NO synthesis are …

Chronic inflammation is a leading cause of neoplastic transformation in many human
cancers and especially in colon cancer (CC), in part due to tumour promotion by nitric oxide …

Nitric oxide (NO), is a ubiquitous, water soluble, free radical gas, which plays key role in
various physiological as well as pathological processes. Over past decades, NO has …