Viral respiratory pathogens and lung injury

N Clementi, S Ghosh, M De Santis… - Clinical microbiology …, 2021 - Am Soc Microbiol
Several viruses target the human respiratory tract, causing different clinical manifestations
spanning from mild upper airway involvement to life-threatening acute respiratory distress …

Respiratory viruses: their importance and lessons learned from COVID-19

C Cilloniz, CM Luna, JC Hurtado… - European …, 2022 - Eur Respiratory Soc
Respiratory virus infection can cause severe illnesses capable of inducing acute respiratory
failure that can progress rapidly to acute respiratory distress syndrome (ARDS). ARDS is …

Mitigating future respiratory virus pandemics: new threats and approaches to consider

GC Gray, ER Robie, CJ Studstill, CL Nunn - Viruses, 2021 - mdpi.com
Despite many recent efforts to predict and control emerging infectious disease threats to
humans, we failed to anticipate the zoonotic viruses which led to pandemics in 2009 and …

Coronavirus infections and immune responses

G Li, Y Fan, Y Lai, T Han, Z Li, P Zhou… - Journal of medical …, 2020 - Wiley Online Library
Coronaviruses (CoVs) are by far the largest group of known positive‐sense RNA viruses
having an extensive range of natural hosts. In the past few decades, newly evolved …

The host immune response in respiratory virus infection: balancing virus clearance and immunopathology

AH Newton, A Cardani, TJ Braciale - Seminars in immunopathology, 2016 - Springer
The respiratory tract is constantly exposed to the external environment, and therefore, must
be equipped to respond to and eliminate pathogens. Viral clearance and resolution of …

Pathogenesis of viral infection in exacerbations of airway disease

AI Ritchie, HA Farne, A Singanayagam… - Annals of the …, 2015 - atsjournals.org
Chronic airway diseases are a significant cause of morbidity and mortality worldwide, and
their prevalence is predicted to increase in the future. Respiratory viruses are the most …

Severe infections due to respiratory viruses

C Cilloniz, JM Pericas, JR Rojas… - Seminars in Respiratory …, 2022 - thieme-connect.com
Severe viral infections may result in severe illnesses capable of causing acute respiratory
failure that could progress rapidly to acute respiratory distress syndrome (ARDS), related to …

Viral and bacterial co-infections in the lungs: dangerous liaisons

J Oliva, O Terrier - Viruses, 2021 - mdpi.com
Respiratory tract infections constitute a significant public health problem, with a therapeutic
arsenal that remains relatively limited and that is threatened by the emergence of antiviral …

Respiratory viral infections in exacerbation of chronic airway inflammatory diseases: novel mechanisms and insights from the upper airway epithelium

KS Tan, RL Lim, J Liu, HH Ong, VJ Tan… - Frontiers in cell and …, 2020 - frontiersin.org
Respiratory virus infection is one of the major sources of exacerbation of chronic airway
inflammatory diseases. These exacerbations are associated with high morbidity and even …

Modulation of the host response as a therapeutic strategy in severe lung infections

E Latreille, WL Lee - Viruses, 2023 - mdpi.com
Respiratory pathogens such as influenza and SARS-CoV-2 can cause severe lung
infections leading to acute respiratory distress syndrome (ARDS). The pathophysiology of …