Efficacy and safety of saxagliptin in drug‐naïve Asian patients with type 2 diabetes mellitus: a randomized controlled trial

CY Pan, W Yang, C Tou… - … research and reviews, 2012 - Wiley Online Library
Background Few studies have assessed the use of new oral anti‐diabetic agents in Asian
populations. This study assesses the efficacy and safety of saxagliptin versus placebo in …

Efficacy and safety of saxagliptin added to metformin in Asian people with type 2 diabetes mellitus: a randomized controlled trial

W Yang, CY Pan, C Tou, J Zhao… - Diabetes research and …, 2011 - Elsevier
AIM: To assess efficacy and safety of saxagliptin added to metformin versus placebo plus
metformin in Asian patients with type 2 diabetes mellitus (T2DM) and inadequate glycemic …

Efficacy and safety of saxagliptin in combination with metformin as initial therapy in C hinese patients with type 2 diabetes: R esults from the START study, a …

J Dou, J Ma, J Liu, C Wang, E Johnsson… - Diabetes, Obesity …, 2018 - Wiley Online Library
Aim To assess the efficacy and safety of saxagliptin plus metformin over 24 weeks in
pharmacotherapy‐naïve Chinese patients with type 2 diabetes mellitus and inadequate …

Effect of saxagliptin monotherapy in treatment-naive patients with type 2 diabetes

J Rosenstock, C Aguilar-Salinas, E Klein… - … medical research and …, 2009 - Taylor & Francis
Objective: To evaluate the efficacy and safety of once-daily saxagliptin monotherapy in
treatment-naïve patients with type 2 diabetes (T2D) and inadequate glycemic control …

Saxagliptin: a clinical review in the treatment of type 2 diabetes mellitus

DS Kania, JD Gonzalvo, ZA Weber - Clinical therapeutics, 2011 - Elsevier
BACKGROUND: Some conventional therapies for type 2 diabetes mellitus (T2DM) fail to
address the progressive nature of the disease, and as a result, they may become ineffective …

Tolerability of saxagliptin in patients with inadequately controlled type 2 diabetes: results from 6 phase III studies

JA Davidson - Journal of Managed Care Pharmacy, 2014 - jmcp.org
BACKGROUND: Oral antihyperglycemic drugs used to treat type 2 diabetes mellitus (T2DM)
vary in safety and tolerability. Treatment-related hypoglycemia and weight gain can …

Efficacy and safety of saxagliptin combination therapy in US patients with type 2 diabetes

C Karyekar, M Donovan, E Allen, D Fleming… - Postgraduate …, 2011 - Taylor & Francis
Background: The mechanism of action of dipeptidyl peptidase-4 inhibitors, such as
saxagliptin, makes them suitable for combination therapy in type 2 diabetes mellitus (T2DM) …

A randomized controlled trial of the efficacy and safety of saxagliptin as add‐on therapy in patients with type 2 diabetes and inadequate glycaemic control on …

RG Moses, S Kalra, D Brook, J Sockler… - Diabetes, Obesity …, 2014 - Wiley Online Library
Aims To evaluate the efficacy and safety of saxagliptin as add‐on therapy in adults with type
2 diabetes with inadequate glycaemic control on metformin plus a sulphonylurea. Methods …

Saxagliptin: a review of its use as combination therapy in the management of type 2 diabetes mellitus in the EU

LPH Yang - Drugs, 2012 - Springer
Saxagliptin (Onglyza™) is a dipeptidyl peptidase 4 inhibitor widely approved for the
treatment of type 2 diabetes mellitus. In the EU, saxagliptin is indicated as combination …

Long‐term 4‐year safety of saxagliptin in drug‐naive and metformin‐treated patients with type 2 diabetes

J Rosenstock, JL Gross, C Aguilar‐Salinas… - Diabetic …, 2013 - Wiley Online Library
Aims To evaluate the safety of saxagliptin±metformin over 4 years in patients with Type 2
diabetes mellitus. Methods Drug‐naive (n= 401; study 11) or metformin‐treated (n= 743; …