Advances in microneedle-based transdermal delivery for drugs and peptides

K Aich, T Singh, S Dang - Drug Delivery and Translational Research, 2022 - Springer
Transdermal drug delivery is a viable and clinically proven route of administration. This route
specifically requires overcoming the mechanical barrier provided by the Stratum Corneum of …

Effect of polymer microneedle pre-treatment on drug distributions in the skin in vivo

YY Hao, Y Yang, QY Li, XP Zhang, CB Shen… - Journal of Drug …, 2020 - Taylor & Francis
Solid microneedles (MNs) represent a useful tool for enhancing skin permeability by
creating microchannels that provide a drug delivery route. To achieve the solid polymer MNs …

Characterization of microchannels created by metal microneedles: formation and closure

H Kalluri, CS Kolli, AK Banga - The AAPS journal, 2011 - Springer
Transdermal delivery of therapeutic agents for cosmetic therapy is limited to small and
lipophilic molecules by the stratum corneum barrier. Microneedle technology overcomes this …

Microneedles for transdermal drug delivery

EM Migdadi, RF Donnelly - Imaging Technologies and …, 2019 - Wiley Online Library
Transdermal drug delivery includes application of drug (s) to the skin for systemic effects.
However, relatively few drugs possess the requisite characteristics to passively traverse the …

Engineered microneedle patches for controlled release of active compounds: recent advances in release profile tuning

R Jamaledin, P Makvandi, CKY Yiu… - Advanced …, 2020 - Wiley Online Library
Transdermal microneedle patches have attracted significant attention in the medical arena
over the last decade as alternatives to traditional drug delivery methods. Microneedle …

Microneedles and transdermal drug delivery

H Kalluri, AK Banga - Journal of Drug Delivery Science and Technology, 2009 - Elsevier
Transdermal delivery has become a popular route of drug delivery in recent years. However,
permeation of drugs through skin is limited to small lipophilic molecules. Microneedle …

[HTML][HTML] Progress in microneedle-mediated protein delivery

R Jamaledin, C Di Natale, V Onesto… - Journal of clinical …, 2020 - mdpi.com
The growing demand for patient-compliance therapies in recent years has led to the
development of transdermal drug delivery, which possesses several advantages compared …

Polymeric microneedles for transdermal drug delivery-a review of recent studies

Z Karim, P Karwa, SRR Hiremath - Journal of Drug Delivery Science and …, 2022 - Elsevier
Transdermal drug delivery is contemplated as one of the top appealing routes for
pharmaceutically active ingredients administration owing to the several benefits, specifically …

[PDF][PDF] Microneedles: An innovative approach to transdermal delivery-a review

N Akhtar - Int. J. Pharm. Pharm. Sci, 2014 - scholar.archive.org
Transdermal delivery holds a promising carrier in the transport of drugs to get direct access
across the skin deep into the systemic circulation.. It has attracted many researchers due to …

Stimuli-responsive microneedles as a transdermal drug delivery system: a demand-supply strategy

BHJ Gowda, MG Ahmed, A Sahebkar, Y Riadi… - …, 2022 - ACS Publications
Microneedles are one of the most prominent approaches capable of physically disrupting
the stratum corneum without devastating the deeper tissues to deliver both small molecules …