The most promising microneedle device: present and future of hyaluronic acid microneedle patch

H Kang, Z Zuo, R Lin, M Yao, Y Han, J Han - Drug delivery, 2022 - Taylor & Francis
Microneedle patch (MNP) is an alternative to the oral route and subcutaneous injection with
unique advantages such as painless administration, good compliance, and fewer side …

Challenges and strategies in developing microneedle patches for transdermal delivery of protein and peptide therapeutics

F Wu, S Yang, W Yuan, T Jin - Current pharmaceutical …, 2012 - ingentaconnect.com
The birth of microneedles, an array of needles sufficiently long to penetrate epidermis but
small enough to do not cause skin injury and pain feeling, has offered a highly promising …

Polymer microneedles for transdermal drug delivery

JW Lee, MR Han, JH Park - Journal of drug targeting, 2013 - Taylor & Francis
A microneedle system has been developed to deliver chemical and biological agents
through the stratum corneum, which is the main barrier to drug delivery. Recently …

How can microneedles overcome challenges facing transdermal drug delivery?

RF Donnelly - Therapeutic Delivery, 2017 - Future Science
Editorial Donnelly has concentrated on hydrophilic drugs. This is hardly surprising, due to
the ever-expanding list of therapeutic macromolecules of biological origin that have to be …

Effect of microneedle geometry and supporting substrate on microneedle array penetration into skin

JS Kochhar, WJ Soon, J Choi, S Zou, L Kang - Journal of Pharmaceutical …, 2013 - Elsevier
Microneedles are being fast recognized as a useful alternative to injections in delivering
drugs, vaccines, and cosmetics transdermally. Owing to skin's inherent elastic properties …

Microneedles in drug delivery

R Mahato - … nanotechnologies for diagnostics, drug delivery and …, 2017 - Elsevier
Transdermal drug delivery offers a number of advantages due to its minimally invasive and
painless approach as well as the avoidance of first-pass drug metabolism and …

Dissolving microneedle patches loaded with amphotericin B microparticles for localised and sustained intradermal delivery: Potential for enhanced treatment of …

K Peng, LK Vora, IA Tekko, AD Permana… - Journal of Controlled …, 2021 - Elsevier
Fungal infections affect millions of people globally and are often unreceptive to conventional
topical or oral preparations because of low drug bioavailability at the infection site, lack of …

Unravelling the role of microneedles in drug delivery: Principle, perspectives, and practices

MR Babu, S Vishwas, R Khursheed, V Harish… - Drug Delivery and …, 2024 - Springer
In recent year, the research of transdermal drug delivery systems has got substantial
attention towards the development of microneedles (MNs). This shift has occurred due to …

Polymer-coated polymeric (PCP) microneedles for controlled dermal delivery of 5-fluorouracil

AV Matadh, D Jakka, SG Pragathi, S Rangappa… - AAPS …, 2022 - Springer
Polymeric microneedles were prepared with Polyvinyl Pyrrolidone (PVP) K-30 using the
mold casting technique. The core microneedles were coated with Eudragit E-100 by dip and …

Optimizing microneedle arrays to increase skin permeability for transdermal drug delivery

B Al‐Qallaf, DB Das - Annals of the New York Academy of …, 2009 - Wiley Online Library
Improving drug permeability in the skin is one of the most important issues for designing new
methods of transdermal drug delivery. Consequently, many techniques have been proposed …