Efficacy of niclosamide vs placebo in SARS-CoV-2 respiratory viral clearance, viral shedding, and duration of symptoms among patients with mild to moderate COVID …
DM Cairns, D Dulko, JK Griffiths, Y Golan… - JAMA network …, 2022 - jamanetwork.com
Importance Oral anthelmintic niclosamide has potent in vitro antiviral activity against SARS-
CoV-2. Repurposed niclosamide could be a safe and efficacious COVID-19 therapy …
CoV-2. Repurposed niclosamide could be a safe and efficacious COVID-19 therapy …
A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19
V Backer, U Sjöbring, J Sonne, A Weiss… - The Lancet Regional …, 2021 - thelancet.com
Background Coronavirus disease 19 (COVID-19) is spreading globally and treatment
options remain limited. A formulation of niclosamide, a potent anti-SARS-CoV-2 agent and a …
options remain limited. A formulation of niclosamide, a potent anti-SARS-CoV-2 agent and a …
Niclosamide shows strong antiviral activity in a human airway model of SARS-CoV-2 infection and a conserved potency against the Alpha (B. 1.1. 7), Beta (B. 1.351) …
SARS-CoV-2 variants are emerging with potential increased transmissibility highlighting the
great unmet medical need for new therapies. Niclosamide is a potent anti-SARS-CoV-2 …
great unmet medical need for new therapies. Niclosamide is a potent anti-SARS-CoV-2 …
Broad spectrum antiviral agent niclosamide and its therapeutic potential
The recent outbreak of coronavirus disease 2019 (COVID-19) highlights an urgent need for
therapeutics. Through a series of drug repurposing screening campaigns, niclosamide, an …
therapeutics. Through a series of drug repurposing screening campaigns, niclosamide, an …
[HTML][HTML] A randomised controlled trial of effectiveness and safety of Niclosamide as add on therapy to the standard of care measures in COVID-19 management
Background COVID-19 pandemic has ignited the urge for repurposing old drugs as
candidate antiviral medicines to treat novel challenges of viral infections. Niclosamide (NCS) …
candidate antiviral medicines to treat novel challenges of viral infections. Niclosamide (NCS) …
Niclosamide—a promising treatment for COVID‐19
Vaccines have reduced the transmission and severity of COVID‐19, but there remains a
paucity of efficacious treatment for drug‐resistant strains and more susceptible individuals …
paucity of efficacious treatment for drug‐resistant strains and more susceptible individuals …
Niclosamide for Covid-19: bridging the gap
Aim/purpose Niclosamide (NCL) is an anthelminthic drug, which is widely used to treat
various diseases due to its pleiotropic anti-inflammatory and antiviral activities. NCL …
various diseases due to its pleiotropic anti-inflammatory and antiviral activities. NCL …
Plausible mechanisms of Niclosamide as an antiviral agent against COVID-19
SKSS Pindiprolu, SH Pindiprolu - Medical hypotheses, 2020 - Elsevier
Abstract Corona virus disease 2019 (COVID-19) pandemic caused 18 440 deaths world
wide as of 25 March 2020 and posing a serious threat to public health. There is a need …
wide as of 25 March 2020 and posing a serious threat to public health. There is a need …
A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus
There is an urgent need for an effective, oral, direct-acting therapeutic to block transmission
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent progression …
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent progression …
Effect of molnupiravir on biomarkers, respiratory interventions, and medical services in COVID-19: a randomized, placebo-controlled trial
MG Johnson, A Puenpatom, PA Moncada… - Annals of internal …, 2022 - acpjournals.org
Background: In the MOVe-OUT trial, molnupiravir showed a clinically meaningful reduction
in the risk for hospitalization or death in adults with mild to moderate COVID-19 and risk …
in the risk for hospitalization or death in adults with mild to moderate COVID-19 and risk …
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