The dorsal striatum is a key node for many neurobiological processes such as motor activity,
cognitive functions, and affective processes. The proper functioning of striatal neurons relies …

The striatum is a subcortical area involved in sensorimotor, cognitive and emotional
processes. Adenosine A2A receptors (A2ARs) are highly expressed in the striatum, and their …

J. Neurochem.(2011) 116, 273–280. Abstract An interaction between adenosine A2A
receptors (A2ARs) and cannabinoid CB1 receptors (CB1Rs) has been consistently reported …

Background and Purpose Both cannabinoid CB 1 and adenosine A2A receptors (CB1
receptors and A2A receptors) control synaptic transmission at corticostriatal synapses, with …

Abstract Adenosine A2A receptors (A2 AR s) and cannabinoid CB 1 receptors (CB 1Rs) are
highly expressed in the striatum, where they functionally interact and form A2A/CB 1 …

Adenosine and endocannabinoids are very ubiquitous non‐classical neurotransmitters that
exert a modulatory role on the transmission of other more 'classical'neurotransmitters. In this …

Abstract Adenosine A2A, cannabinoid CB1 and metabotropic glutamate 5 (mGlu5) receptors
are all highly expressed in the striatum. The aim of the present work was to investigate …

Adenosine plays a very significant role in modulating striatal glutamatergic and
dopaminergic neurotransmission. In the present essay we first review the extensive …

At present, clinical interest in the plant-derived cannabinoid compound cannabidiol (CBD) is
rising exponentially, since it displays multiple therapeutic properties. In addition, CBD can …

The introduction of two concepts,“local module” and “receptor heteromer”, facilitates the
understanding of the role of interactions between different neurotransmitters in the brain. In …