To further explore whether immune function and acute phase response are altered during
ageing, the response to a mild inflammatory stress (DT-Polio-Typhim vaccination) was …

It is well known that ageing is associated with various alterations of the lymphoid cell
functions. Although both B and T cell are affected, the last appear to be more sensitive to …

The term immunosenescence is taken to mean the deterioration of immune function seen in
elderly, which is manifested in increased susceptibility to infectious diseases, neoplasias …

Articles in the recent literature document an abnormal antibody response in elderly persons
to influenza vaccination. Several studies have presented evidence to show that immune …

Age-related senescence of T-cell mediated responses is well recognized. This study was
designed to determine how aging affects the T-cell mediated Interleukin 2 (IL2) response to …

There is a general consensus that immune responses are compromised in the elderly [1];
however, old people usually do not suffer from overt immunodeficiency and do not succumb …

The RNA-content of G 1 cells in lectin-stimulated spleen cell cultures of young and aged
NMRI mice was determined by flow cytometry. In spleen cells of aged mice a preferential …

Elderly persons are more susceptible to bacterial and virus infections and neoplasias than
young adults. This is related to an impaired immune response. Lymphocytes of the elderly …

The capacity of lymphocytes obtained from healthy young or old volunteers to produce
interleukin-2 was measured and the results were compared with other measures of immune …

Aging is associated to a progressive establishing of a chronic inflammatory state linked to a
continuous long exposure to antigens. Since IL‐15 stimulates the proliferation of memory T …