Proteolytic processing of human zona pellucida proteins

SML Kiefer, P Saling - Biology of reproduction, 2002 - academic.oup.com
Formation of the egg's extracellular matrix, the zona pellucida, is critical for fertilization and
development of growing embryos. Zona pellucida glycoproteins, ZP1, ZP2, and ZP3, are …

Identification of the carboxyl termini of porcine zona pellucida glycoproteins ZPB and ZPC

N Yonezawa, M Nakano - Biochemical and biophysical research …, 2003 - Elsevier
The extracellular matrix surrounding mammalian oocytes plays important roles in fertilization
and is known as the zona pellucida (ZP). The ZP consists of three glycoproteins, ZPA, ZPB …

Three-dimensional structure of the zona pellucida

DP Green - Reviews of Reproduction, 1997 - rep.bioscientifica.com
The zona pellucida is the extracellular coat that surrounds the mammalian oocyte. It forms a
spherical shell of remarkably uniform thickness (5-10 microns in eutherian mammals). The …

Conserved furin cleavage site not essential for secretion and integration of ZP3 into the extracellular egg coat of transgenic mice

M Zhao, L Gold, AM Ginsberg, LF Liang… - Molecular and Cellular …, 2002 - Taylor & Francis
The extracellular zona pellucida surrounding mammalian eggs is formed by interactions of
the ZP1, ZP2, and ZP3 glycoproteins. Female mice lacking ZP2 or ZP3 do not form a stable …

Mouse zona pellucida glycoproteins mZP2 and mZP3 undergo carboxy-terminal proteolytic processing in growing oocytes

ES Litscher, H Qi, PM Wassarman - Biochemistry, 1999 - ACS Publications
The extracellular coat, or zona pellucida, of the mouse egg consists of three glycoproteins,
called mZP1− 3. The glycoproteins are synthesized and secreted concomitantly by growing …

Features that affect secretion and assembly of zona pellucida glycoproteins during mammalian oogenesis.

L Jovine, H Qi, Z Williams, ES Litscher… - … of Reproduction and …, 2007 - europepmc.org
For sperm to fertilize eggs, they must bind to and penetrate the zona pellucida (ZP) that
surrounds the plasma membrane of all mammalian eggs. The ZP first appears during oocyte …

The human egg's zona pellucida

SK Gupta - Current topics in developmental biology, 2018 - Elsevier
Human zona pellucida (ZP) matrix, a delicate network of thin interconnected filaments, is
primarily composed of four glycoproteins, namely, ZP1, ZP2, ZP3, and ZP4. All four zona …

Mouse zona pellucida genes and glycoproteins

PM Wassarman, L Jovine, ES Litscher - Cytogenetic and Genome …, 2004 - karger.com
The zona pellucida (ZP) is a thick extracellular coat that surrounds all mammalian eggs. The
ZP plays important roles during oogenesis, fertilization, and preimplantation development …

Posttranslational modifications of zona pellucida proteins

N Yonezawa - … Protein Modifications in the Reproductive System, 2014 - Springer
The zona pellucida (ZP), which surrounds the mammalian oocyte, functions in various
aspects of fertilization. The ZP consists of three or four glycoproteins, which are derived from …

Secretion and assembly of zona pellucida glycoproteins by growing mouse oocytes microinjected with epitope-tagged cDNAs for mZP2 and mZP3

H Qi, Z Williams, PM Wassarman - Molecular biology of the cell, 2002 - Am Soc Cell Biol
The zona pellucida (ZP) is a highly organized extracellular coat that surrounds all
mammalian eggs. The mouse egg ZP is composed of three glycoproteins, called mZP1–3 …