Effects of adenosine and γ‐aminobutyric acid a receptor antagonists on N‐methyl‐D‐aspartate induced neurotoxicity in the rat hippocampus

P Robledo, G Ursu, N Mahy - Hippocampus, 1999 - Wiley Online Library
This study investigated the modulatory actions of adenosine and γ‐aminobutyric acid
(GABA) on several aspects of N‐methyl‐d‐aspartate (NMDA)‐induced neurotoxicity …

Influence of caffeine on 3, 4‐methylenedioxymethamphetamine‐induced dopaminergic neuron degeneration and neuroinflammation is age‐dependent

L Frau, G Costa, PF Porceddu… - Journal of …, 2016 - Wiley Online Library
Previous studies have demonstrated that caffeine administration to adult mice potentiates
glial activation induced by 3, 4‐methylenedioxymethamphetamine (MDMA). As …

Sex‐dependent long‐term effects of adolescent exposure to THC and/or MDMA on neuroinflammation and serotoninergic and cannabinoid systems in rats

AB Lopez‐Rodriguez, A Llorente‐Berzal… - British journal of …, 2014 - Wiley Online Library
Background and Purpose Many young people consume ecstasy as a recreational drug and
often in combination with cannabis. In this study, we aimed to mimic human consumption …

[HTML][HTML] Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated …

JH Park, YH Seo, JH Jang, CH Jeong, S Lee… - Journal of …, 2017 - Springer
Background Methamphetamine (METH) is a commonly abused drug that may result in
neurotoxic effects. Recent studies have suggested that involvement of neuroinflammatory …

Influence of CGS 21680, a selective adenosine A2A receptor agonist, on NMDA receptor function and expression in the brain of Huntington's disease mice

A Ferrante, A Martire, M Armida, V Chiodi, A Pézzola… - Brain research, 2010 - Elsevier
The effect of chronic treatment with the selective adenosine A2A receptor agonist CGS
21680 on N-Methyl-d-Aspartate (NMDA) receptor function and expression has been studied …

Evidence that MDMA ('ecstasy') increases cannabinoid CB2 receptor expression in microglial cells: role in the neuroinflammatory response in rat brain

E Torres, MD Gutierrez‐Lopez, E Borcel… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 10.1111/j. 1471‐4159.2010. 06578. x Abstract 3, 4‐
Methylenedioxymethamphetamine (MDMA,'ecstasy') produces selective long‐lasting …

Chronic MDMA induces neurochemical changes in the hippocampus of adolescent and young adult rats: Down-regulation of apoptotic markers

R Garcia-Cabrerizo, MJ García-Fuster - Neurotoxicology, 2015 - Elsevier
While hippocampus is a brain region particularly susceptible to the effects of MDMA, the
cellular and molecular changes induced by MDMA are still to be fully elucidated, being the …

Amphetamine sensitization alters hippocampal neuronal morphology and memory and learning behaviors

LE Arroyo-García, H Tendilla-Beltrán… - Molecular …, 2021 - nature.com
It is known that continuous abuse of amphetamine (AMPH) results in alterations in neuronal
structure and cognitive behaviors related to the reward system. However, the impact of …

[HTML][HTML] MDMA and the Brain: A Short Review on the Role of Neurotransmitters in Neurotoxicity

NS Mustafa, NHA Bakar, N Mohamad… - Basic and clinical …, 2020 - ncbi.nlm.nih.gov
Abstract N-Methyl-3, 4-methylenedioxyamphetamine (MDMA), or ecstasy is a recreational
drug of abuse. It is a synthetic substance that affects the body's systems, which its …

[HTML][HTML] Involvement of metabotropic glutamate receptor 5, AKT/PI3K signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 …

A Shah, PS Silverstein, DP Singh, A Kumar - Journal of neuroinflammation, 2012 - Springer
Methamphetamine (MA) is one of the commonly used illicit drugs and the central nervous
system toxicity of MA is well documented. The mechanisms contributing to this toxicity have …