MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase
JH Anneken, JI Cunningham, SA Collins… - Journal of NeuroImmune …, 2013 - Springer
Methylenedioxymethamphetamine (MDMA; Ecstasy) is a popular drug of abuse with well-
documented acute effects on serotonergic, dopaminergic, and cholinergic transmitter …
documented acute effects on serotonergic, dopaminergic, and cholinergic transmitter …
Oral acetate supplementation attenuates N-methyl D-aspartate receptor hypofunction-induced behavioral phenotypes accompanied by restoration of acetyl-histone …
Rationale Aberrations in cellular acetate-utilization processes leading to global histone
hypoacetylation have been implicated in the etiology of neuropsychiatric disorders like …
hypoacetylation have been implicated in the etiology of neuropsychiatric disorders like …
Combined neuroprotective action of adenosine A1 and cannabinoid CB1 receptors against NMDA-induced excitotoxicity in the hippocampus
A Serpa, I Pinto, L Bernardino… - Neurochemistry …, 2015 - Elsevier
Both adenosine A 1 and cannabinoid CB 1 receptors trigger similar transduction pathways
and protect against neurotoxic insults at the hippocampus, but their combined …
and protect against neurotoxic insults at the hippocampus, but their combined …
Enhanced neurodegeneration after a high dose of methamphetamine in adenosine A3 receptor null mutant mice
H Shen, Y Luo, SJ Yu, Y Wang - Neuroscience, 2011 - Elsevier
Previous reports have indicated that adenosine A3 receptor (A3R) knockout mice are more
sensitive to ischemic or hypoxic brain injury. The purpose of this study was to examine if …
sensitive to ischemic or hypoxic brain injury. The purpose of this study was to examine if …
[HTML][HTML] Carbamazepine Attenuates Astroglial L-Glutamate Release Induced by Pro-Inflammatory Cytokines via Chronically Activation of Adenosine A2A Receptor
M Okada, K Fukuyama, T Shiroyama… - International Journal of …, 2019 - mdpi.com
Carbamazepine (CBZ) binds adenosine receptors, but detailed effects of CBZ on astroglial
transmission associated with adenosine receptor still need to be clarified. To clarify …
transmission associated with adenosine receptor still need to be clarified. To clarify …
MDMA decreases glutamic acid decarboxylase (GAD) 67-immunoreactive neurons in the hippocampus and increases seizure susceptibility: Role for glutamate
CL Huff, RL Morano, JP Herman, BK Yamamoto… - Neurotoxicology, 2016 - Elsevier
Methylenedioxy-methamphetamine (MDMA) is a unique psychostimulant that continues to
be a popular drug of abuse. It has been well documented that MDMA reduces markers of 5 …
be a popular drug of abuse. It has been well documented that MDMA reduces markers of 5 …
Neuronal adenosine A2A receptor overexpression is neuroprotective towards 3-nitropropionic acid-induced striatal toxicity: a rat model of Huntington's disease
MR Domenici, V Chiodi, M Averna, M Armida… - Purinergic …, 2018 - Springer
The A 2A adenosine receptor (A 2A R) is widely distributed on different cellular types in the
brain, where it exerts a broad spectrum of pathophysiological functions, and for which a role …
brain, where it exerts a broad spectrum of pathophysiological functions, and for which a role …
Caffeine enhances astroglia and microglia reactivity induced by 3, 4-methylenedioxymethamphetamine ('ecstasy') in mouse brain
A Khairnar, A Plumitallo, L Frau, N Schintu… - Neurotoxicity …, 2010 - Springer
Abstract Several reports suggest that 3, 4-methylenedioxymethamphetamine (MDMA)
induces neurotoxic effects and gliosis. Since recreational use of MDMA is often associated …
induces neurotoxic effects and gliosis. Since recreational use of MDMA is often associated …
[HTML][HTML] THC prevents MDMA neurotoxicity in mice
C Touriño, A Zimmer, O Valverde - PLoS One, 2010 - journals.plos.org
The majority of MDMA (ecstasy) recreational users also consume cannabis. Despite the
rewarding effects that both drugs have, they induce several opposite pharmacological …
rewarding effects that both drugs have, they induce several opposite pharmacological …
[HTML][HTML] RETRACTED ARTICLE: Gene expression analysis indicates CB1 receptor upregulation in the hippocampus and neurotoxic effects in the frontal cortex 3 …
P Petschner, V Tamasi, C Adori, E Kirilly, RD Ando… - BMC genomics, 2013 - Springer
Abstract Background 3, 4-methylenedioxymethamphetamine (MDMA," ecstasy") is a widely
used recreational drug known to impair cognitive functions on the long-run. Both …
used recreational drug known to impair cognitive functions on the long-run. Both …