The non-competitive AMPA antagonist LY 300168 (GYKI 53655) attenuates AMPA-induced hippocampal injury in neonatal rodents

XH Liu, P Wang, JDE Barks - Neuroscience letters, 1997 - Elsevier
In contrast with the neuroprotective efficacy of competitive and non-competitive N-methyl-d-
aspartate (NMDA) antagonists versus NMDA neurotoxicity, reported neuroprotective effects …

[HTML][HTML] Long-term cyclosporine A treatment promotes anxiety-like behavior: possible relation with glutamate signaling in rat hippocampus

MM Cararo-Lopes, DG Souza, M Ganzella… - Journal of Affective …, 2022 - Elsevier
Background Chronic immunosuppressive treatment with cyclosporine A (CsA) leads to
multiple side effects, including some that occur in the central nervous system (CNS). This …

Methamphetamine‐induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin

J Gonçalves, S Baptista, T Martins… - European Journal of …, 2010 - Wiley Online Library
Methamphetamine (METH) causes irreversible damage to brain cells leading to
neurological and psychiatric abnormalities. However, the mechanisms underlying life …

Neuroprotection of adenoviral-vector-mediated GDNF expression against kainic-acid-induced excitotoxicity in the rat hippocampus

YM Yoo, CJ Lee, U Lee, YJ Kim - Experimental neurology, 2006 - Elsevier
Glial-cell-line-derived neurotrophic factor (GDNF) is a potent survival factor for several types
of neurons. In the present study, we examined the protective roles of adenoviral-vector …

Neurotoxic effects of MDMA (ecstasy) on the developing rodent brain

M Dzietko, M Sifringer, J Klaus, S Endesfelder… - Developmental …, 2010 - karger.com
The incidence of methamphetamine abuse is particularly high in adolescents and is a
common problem among women of childbearing age, leading to an increasing number of …

Nuclear factor κB is a critical determinant in N‐methyl‐d‐aspartate receptor‐mediated neuroprotection

RH Lipsky, K Xu, D Zhu, C Kelly… - Journal of …, 2001 - Wiley Online Library
The role of a nuclear factor κB (NF‐κB) in NMDA receptor‐mediated neuroprotection is not
known. A candidate sequence from the 5′ flanking region of exon 3 of the rat brain‐derived …

Ginsenosides attenuate methamphetamine-induced behavioral side effects in mice via activation of adenosine A2A receptors: possible involvements of the striatal …

EJ Shin, T Nabeshima, HW Suh, WK Jhoo… - Behavioural brain …, 2005 - Elsevier
Current evidence suggests that ginsenosides inhibit methamphetamine (MA)-induced
changes in behavior, but the precise mechanisms that underlie this effect are yet to be …

[HTML][HTML] Theta/gamma co-modulation disruption after NMDAr blockade by MK-801 is associated with spatial working memory deficits in mice

P Abad-Perez, FJ Molina-Payá, L Martínez-Otero… - Neuroscience, 2023 - Elsevier
Abnormal N-methyl-D-aspartate receptor (NMDAr) function has been linked to
oscillopathies, psychosis, and cognitive dysfunction in schizophrenia (SCZ). Here, we …

[HTML][HTML] Switching of N-methyl-D-aspartate (NMDA) receptor-favorite intracellular signal pathways from ERK1/2 protein to p38 mitogen-activated protein kinase leads …

L Xiao, C Hu, C Feng, Y Chen - Journal of Biological Chemistry, 2011 - ASBMB
Excitotoxicity mediated by overactivation of N-methyl-d-aspartate receptors (NMDARs) has
been implicated in a variety of neuropathological conditions in the central nervous system …

(+) MK-801 prevents the DDC-induced enhancement of MPTP toxicity in mice

F Vaglini, F Fascetti, F Fornai, R Maggio, GU Corsini - Brain research, 1994 - Elsevier
In order to reach deeper insight into the mechanism of diethyldithiocarbamate (DDC)-
induced enhancement of MPTP toxicity in mice, MK-801, a non-competitive antagonist of …