[HTML][HTML] The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells
E Eljaschewitsch, A Witting, C Mawrin, T Lee… - Neuron, 2006 - cell.com
Endocannabinoids are released after brain injury and believed to attenuate neuronal
damage by binding to CB 1 receptors and protecting against excitotoxicity. Such excitotoxic …
damage by binding to CB 1 receptors and protecting against excitotoxicity. Such excitotoxic …
[HTML][HTML] Anxiolytic effect of exogenous ketone supplementation is abolished by adenosine A1 receptor inhibition in Wistar Albino Glaxo/Rijswijk rats
Z Kovács, DP D'Agostino, C Ari - Frontiers in Behavioral …, 2018 - frontiersin.org
Anxiety disorders are one of the most common mental health problems worldwide, but the
exact pathophysiology remains largely unknown. It has been demonstrated previously that …
exact pathophysiology remains largely unknown. It has been demonstrated previously that …
Progression and persistence of neurotoxicity induced by MDMA in dopaminergic regions of the mouse brain and association with noradrenergic, GABAergic, and …
Abstract The amphetamine-related drug 3, 4methylenedioxymethamphetamine (MDMA) is
known to induce neurotoxic damage in dopaminergic regions of the mouse brain. In order to …
known to induce neurotoxic damage in dopaminergic regions of the mouse brain. In order to …
Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by β-amyloid peptides via p38 mitogen-activated protein kinase pathway
PM Canas, LO Porciúncula, GMA Cunha… - Journal of …, 2009 - Soc Neuroscience
Alzheimer's disease (AD) is characterized by memory impairment, neurochemically by
accumulation of β-amyloid peptide (namely Aβ1-42) and morphologically by an initial loss of …
accumulation of β-amyloid peptide (namely Aβ1-42) and morphologically by an initial loss of …
Adenosine A2A receptor agonist polydeoxyribonucleotide ameliorates short-term memory impairment by suppressing cerebral ischemia-induced inflammation via …
IG Ko, JJ Jin, L Hwang, SH Kim, CJ Kim, JW Jeon… - PLoS …, 2021 - journals.plos.org
Cerebral ischemia causes tissue death owing to occlusion of the cerebral blood vessels,
and cerebral ischemia activates mitogen-activated protein kinase (MAPK) and induces …
and cerebral ischemia activates mitogen-activated protein kinase (MAPK) and induces …
Adenosine A2A receptor inactivation alleviates early-onset cognitive dysfunction after traumatic brain injury involving an inhibition of tau hyperphosphorylation
ZA Zhao, Y Zhao, YL Ning, N Yang, Y Peng, P Li… - Translational …, 2017 - nature.com
Tau is a microtubule-associated protein, and the oligomeric and hyperphosphorylated forms
of tau are increased significantly after neurotrauma and considered important factors in …
of tau are increased significantly after neurotrauma and considered important factors in …
Adenosine A2A receptor blockade reverts hippocampal stress-induced deficits and restores corticosterone circadian oscillation
VL Batalha, JM Pêgo, BM Fontinha, AR Costenla… - Molecular …, 2013 - nature.com
Maternal separation (MS) is an early life stress model that induces permanent changes in
the central nervous system, impairing hippocampal long-term potentiation (LTP) and spatial …
the central nervous system, impairing hippocampal long-term potentiation (LTP) and spatial …
Enhanced tau phosphorylation in the hippocampus of mice treated with 3, 4-methylenedioxymethamphetamine (“Ecstasy”)
CL Busceti, F Biagioni, B Riozzi… - Journal of …, 2008 - Soc Neuroscience
3, 4-Methylenedioxymethamphetamine (MDMA)(“Ecstasy”) produces neurotoxic effects,
which result into an impairment of learning and memory and other neurological …
which result into an impairment of learning and memory and other neurological …
Genetic and pharmacological inactivation of the adenosine A2A receptor attenuates 3‐nitropropionic acid‐induced striatal damage
Abstract Adenosine A2A receptor (A2AR) antagonism attenuates 1‐methyl‐4‐phenyl‐1, 2, 3,
6‐tetrahydropyridine‐induced dopaminergic neurodegeneration and quinolinic acid …
6‐tetrahydropyridine‐induced dopaminergic neurodegeneration and quinolinic acid …
Persistent MDMA‐induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice
Acute administration of repeated doses of 3, 4‐methylenedioxymethamphetamine (MDMA,
ecstasy) dramatically reduces striatal dopamine (DA) content, tyrosine hydroxylase (TH) …
ecstasy) dramatically reduces striatal dopamine (DA) content, tyrosine hydroxylase (TH) …